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This study found that DHEA significantly inhibited growth and induced autophagy in a mouse melanoma cell line, but showed only muffled inhibition and induced apoptosis in a human melanoma cell line.

This paper discusses the methods and challenges of postmarketing surveillance for new antiepileptic drugs, emphasizing the necessity of such data collection to identify adverse effects and assess drug effectiveness beyond initial trials.

This case report identifies necrolytic migratory erythema associated with a glucagonoma in a 40-year-old man, presenting with distinct skin lesions, weight loss, and diarrhea.

This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.

This study found that progression ads are more persuasive for individuals with a weak fresh start mindset, whereas before/after ads are more effective for those with a strong fresh start mindset.

This study suggests that β-Catenin and extracellular matrix components interact in a regulatory loop to influence fibroblast behavior and wound repair properties in dermal tissue.

This review presents a comprehensive evaluation of medical reasoning using large language models, highlighting a significant gap between exam-level performance and true clinical decision-making accuracy.

This study found that para-phenylenediamine induces cytotoxic effects in normal human hair dermal papilla cells by altering microRNA expression and causing cell death, cell cycle arrest, and oxidative stress.

This study developed a new clustering model to improve detection of drug-induced cognitive disorder risk signals, finding that it identified drugs with moderate risk signals, like Carbidopa/Levodopa, missed by traditional methods, enhancing clinical assessment comprehensiveness.

This study found that inhibiting EGFR and MEK in hair follicles may lead to a partial collapse of the immune privilege in the follicles and increased secretion of IL-33.

This review discusses the critical parameters for MALDI IMS sample preparation in skin analysis and highlights its applications in wound healing, neoplasia, and infection research, but reports no new clinical results.

This study identified a subpopulation of neural crest-derived progenitor cells in human corneal endothelial tissue from normal and Fuchs endothelial corneal dystrophy donors, which may have potential for future cell therapy development.

This study demonstrated that CD anisotropy effectively distinguishes between two polymorphs of finasteride with nearly identical electronic circular dichroism spectra, using imaging and simulated spectra to uncover unique signatures that traditional methods miss.

This study found that treating permed hair with diethylene glycol monoethylether significantly reduced the formation of split ends, making it similar to untreated normal hair in terms of split ends generation.

The study reported that Demodex musculi infestation was notably higher in immunodeficient mice, while infested immunocompetent mice, particularly the BALB/c strain, showed increased IgE levels and developed alopecia over time.

This study found that combining AMD-3100 with FK506 in subimmunosuppressive doses enhanced stem cell release from bone marrow, resulting in 25% faster epithelialization in excisional wounds in rats and mice.

This review examines how mathematical modeling of the MAPK pathway, enhanced by single-cell proteomic data, improves understanding of regulatory mechanisms, predicts system behavior, and guides experimental research, emphasizing recent developments in modeling and inference.

This article reviews confocal microscopy findings in trichoepithelioma and desmoplastic trichoepithelioma, noting similarities with histological features, but it provides no new clinical results.

This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.

This study developed a two-step diagnostic model using transcriptome biomarkers from hair follicles to improve the accuracy of methamphetamine use disorder diagnosis, achieving high prediction accuracy in distinguishing non-recovered and almost-recovered patients from healthy controls.

This study investigated the effects of intensive hair dye use in mixed-breed dogs and found changes in the cuticle of the hair shaft and the epidermis using scanning electron microscopy.

This report describes an exceptionally rare adrenal neoplasm in a post-menopausal woman that exclusively secreted DHEA-S, with significant serum level reduction following adrenalectomy.

This case series reports that electrochemotherapy with intravenous bleomycin effectively resolved cutaneous mast cell tumors in four cats, showing no tumor recurrence during follow-up, except for new lesions in one cat, and minimal local toxicity.

This study found that gastrodin promotes the XIAP-DDRGK1 pathway in noise-exposed mice, reducing hearing loss by enhancing ER-phagy and cochlear cell survival.

This study observed that a wearable electric stimulation device significantly promoted hair regeneration in rats and mice, outperforming conventional pharmacological treatments and enhancing growth factor secretion.

This study developed a composite product from decellularized human placental connective tissue matrix and placental extract, finding that the combination showed improved biochemical and mechanical properties compared to each component alone, suggesting its potential use for treating chronic and deeper wounds.

This article discusses the increasing use of follicular unit extraction in hair transplant surgery and presents no new research findings.

In this study, researchers developed and optimized ethanol-free microemulsion systems for transdermal finasteride delivery, finding that the predicted formulations closely matched their physical and chemical characteristics, potentially reducing adverse effects compared to oral administration.

This review describes the edge out punch for follicular unit excision, which may reduce follicle transection with its thicker walls and internal bevel design compared to other punch shapes, but reports no new clinical results.