research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
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research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases
EDA signaling is linked to skin disorders, various cancers, and liver disease.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Cost-Effectively Dissecting the Genetic Architecture of Complex Wool Traits in Rabbits by Low-Coverage Sequencing
Low-coverage sequencing is a cost-effective way to find genetic factors affecting rabbit wool traits.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth
Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Trace Element Zinc and Skin Disorders
Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research Association Between the Serum Estrone-to-Estradiol Ratio and Parameters Related to Glucose Metabolism and Insulin Resistance in Women With Polycystic Ovary Syndrome
Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research Proteomics as a Tool to Improve Novel Insights into Skin Diseases: What We Know and Where We Should Be Going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study
Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
Certain genes are linked to the quality of cashmere in goats.
research Pharmacological Therapeutics in Androgenetic Alopecia
Minoxidil and finasteride are effective for treating hair loss, with dutasteride showing potential but with side effects.
research Aging Skin and Non-Surgical Procedures: A Basic Science Overview
Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
research The Role of the Gut Microbiome and Microbial Dysbiosis in Common Skin Diseases
Gut health affects skin diseases, and probiotics might help.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research Adverse Reactions to Biologic Medications Used in Allergy and Immunology Diseases
Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.
research The Expanding Impact of T-Regulatory Cells in Skin Health
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research Treatment of Crohn's Disease and Concomitant Alopecia Areata With Tofacitinib
Tofacitinib successfully treated hair loss in a Crohn's disease patient who previously used adalimumab.
research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Development of the First Health-Related Quality of Life Questionnaires in Arabic for Women with Polycystic Ovary Syndrome: Creation and Reliability Analysis of PCOSQoL-47 and PCOSQoL-42
Two new reliable Arabic questionnaires for measuring quality of life in women with PCOS were created, one for married and one for unmarried women.
research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies
3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
research Apoptosis in Hair and Skin: A Review
The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
research A Comparative Study of Fractional CO2 Laser with Topical Triamcinolone Acetonide Versus Intralesional Triamcinolone Acetonide in the Treatment of Alopecia Areata
Fractional CO2 laser with topical triamcinolone is more effective and safer for treating alopecia areata than intralesional triamcinolone.
research Cannabinoids and Their Receptors in Skin Diseases
Cannabinoids might help treat skin problems but more research is needed to be sure.
research The Clinical Course and Outcomes of SARS-CoV-2 Virus Infection in Children: A 24-Week Follow-Up Study in Sulaimaniyah, Iraq
Most children recovered from COVID-19 in 4 weeks, but some experienced long-term symptoms, especially older kids.
research Skin Applications of Cannabidiol: Sources, Effects, Delivery Systems, Marketed Formulations and Safety
CBD may improve skin and hair health, but its effective use and safety need more research.
research Commensal Microbiome Promotes Hair Follicle Regeneration by Inducing Keratinocyte HIF-1α Signaling and Glutamine Metabolism
The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.