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In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.

Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.

This study observed that Egyptian patients with discoid lupus erythematosus have significantly lower serum vitamin D3 and antioxidant levels compared to healthy controls, suggesting potential benefits of vitamin D3 and antioxidant supplementation.

Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.

This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.

This study demonstrated that caffeine, minoxidil, and the HIF-1α-stimulating agent deferiprone significantly enhanced dermal papilla cell proliferation in a 3D culture model, suggesting deferiprone as a potential alternative to minoxidil.

This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.

This laboratory study found that dendrobium officinale polysaccharide (DOP) stimulated hair follicle and hair growth in mice by activating the WNT signaling pathway.

This study found that the opioid system, particularly via the delta opioid receptor, broadly regulates cutaneous mechanosensation, including touch, and suggests targeting this receptor could alleviate injury-induced mechanical hypersensitivity.

This review summarizes the role of Ectodysplasin A signaling in skin appendage development and various diseases, noting potential clinical applications but reporting no new research findings.

This review explores disorders of sex development, emphasizing the need for a systematic, multidisciplinary approach and the benefits of genetic testing for better diagnosis and gender assignment planning, but it reports no new clinical findings.

This review analyzes PDRN's molecular mechanisms and therapeutic applications in anti-aging dermatology but reports no new clinical results, highlighting the need for more standardized protocols and long-term evaluations.

This phase 2a trial evaluated Samcyprone for common wart treatment and found that while a sensitization reaction is necessary for therapeutic response, its level does not predict wart clearance.

This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.

In this study, engineered mice with a mutation similar to that in Olmsted syndrome showed progressive hair loss due to impaired inner root sheath keratinocyte differentiation and stem cell exhaustion.

This study found that stressed dermal fibroblasts significantly increased dopa oxidase activity in melanocytes from hair, skin, and eyes, suggesting the involvement of fibroblast-derived factors like basic Fibroblast Growth Factor.

In this study on Drosophila wings, researchers identified 435 genes with significant expression changes during wing hair morphogenesis, and found new phenotypes for 9 genes through functional validation.

This study analyzed pexidartinib-associated adverse events from FDA data and reported common events such as hepatic issues and systemic reactions. It highlighted sex-specific susceptibilities and reinforced the need for risk mitigation and long-term monitoring in tenosynovial giant cell tumor management.

This study found that in mouse models, the novel NF-κB inhibitor DHMEQ improved symptoms of atopic dermatitis as effectively as tacrolimus or betamethasone.

This study found that cPPARγ and dnPPARγ isoforms are differentially expressed in healthy human skin, suggesting that PPARγ modulators may have compartment-specific effects depending on isoform presence.

This study suggests that D-panthenol may promote hair growth by enhancing cell viability, suppressing apoptosis markers, and elongating the anagen phase in human hair follicle cells.

This study found that in a mouse model, betamethasone dipropionate reduced epidermal thickness while fish oil unexpectedly increased it, validating optical coherence tomography as an effective measurement tool.

This study identified a unique transcriptional signature in occipital hair follicles that may protect them from miniaturization in androgenetic alopecia, using an animal-free model to investigate gene roles.

This study generated a Dct-H2BGFP mouse model that allows for effective identification and isolation of melanocytic cells in vivo, facilitating research into their molecular and biological properties.

This study found that DHEA significantly inhibited growth and induced autophagy in a mouse melanoma cell line, but showed only muffled inhibition and induced apoptosis in a human melanoma cell line.

This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.

This study examined the safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis, finding that it was well tolerated and significantly improved symptoms over 52 weeks, with its safety profile similar to that in adults.

This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.

In this chicken embryo study, E40 hemp seed callus-derived exosomes counteracted DHT-induced inhibition of hair follicle development, suggesting potential for alopecia treatment and hair follicle regeneration.

This study found that the herbal extract HX109 promoted hair growth in mice by increasing cell viability and enhancing hair regrowth, with the effects increasing as doses rose.