53 citations
,
September 2013 in “Journal of Investigative Dermatology” This study suggests that cultured hair follicle dermal sheath cup cells exhibit immune privilege properties, partly through the expression of PD-L1, which impacts co-cultured immune cells' behavior.
29 citations
,
August 2011 in “PubMed” This study found that selected polymeric pretreatments on hair can significantly reduce breakage and protect against thermal damage from hot flat irons by maintaining cuticle integrity and moisture.
6 citations
,
November 2023 in “JCI Insight” In mouse models, this study showed that transplanted dermal papilla and dermal sheath cells can integrate into hair follicles, promoting hair growth and extended anagen phases, with their effectiveness influenced by factors such as immune response and cell passage number.
5 citations
,
September 2023 in “Molecules” This review examines physical methods like electron paramagnetic resonance spectroscopy, Raman spectroscopy, and differential scanning calorimetry, highlighting their complementary capabilities in analyzing biomolecular structures and mycobacterial interactions with reactive oxygen species and antioxidants.
4 citations
,
March 2008 in “Korean Journal of Chemical Engineering” Mesenchymal cells can significantly boost human hair growth and longevity.
40 citations
,
June 2019 in “Biochemical and Biophysical Research Communications” This study demonstrated that combining the Wnt/β-catenin activator CHIR99021 with 3D spheroid culture effectively enriched hair follicle formation in reconstituted human skin.
13 citations
,
August 2013 in “Journal of pharmaceutical sciences” This study found that a transdermal delivery system using 3% azone and P407 gel may enhance the skin permeation of doxazosin and finasteride for treating benign prostatic hyperplasia.
2 citations
,
January 2023 in “International Journal of Biological Sciences” In this study, miR-221 was identified as a key factor in androgenetic alopecia pathogenesis due to its role in suppressing hair growth by interacting with androgen receptors and affecting related pathways.
1 citations
,
January 2009 in “Journal of Dermatology and Venereology” This study found that cells from the upper hair follicle exhibited more active growth compared to other segments in vitro, suggesting their potential as a source of hair follicle stem cells.
1 citations
,
January 2007 in “Heterocyclic Communications” This study reports a new method for selectively synthesizing finasteride Form-I in good yield using water as an ecofriendly solvent at room temperature.
October 2024 in “UNESP Institutional Repository (São Paulo State University)” This study investigated the effects of ammonium thioglycolate and amino methylpropanol hair straightening followed by permanent coloring, finding significant physical and chemical changes to both the cuticle and cortex of hair fibers.
June 2023 in “Historical records of Australian science/Historical Records of Australian Science” This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.
343 citations
,
October 2015 in “Endocrine Practice” This review discusses the diagnostic criteria and management strategies for Polycystic Ovary Syndrome (PCOS) and highlights the need for comprehensive clinical assessment, but does not report new clinical findings.
May 2024 in “Brain disorders” In this animal study, agmatine exhibited a protective effect against seizures related to hormone fluctuations, with results suggesting that its anticonvulsant properties may involve interactions with central neurosteroids in female rats experiencing progesterone withdrawal.
May 2022 in “Голова и шея.” In this pilot study, researchers observed that low-intensity laser radiation at 445±40 nm increased the temperature of gingival tissues in Wistar rats by 8.37°C without exceeding the safety threshold, suggesting potential for clinical trials.
May 2022 in “Голова и шея.” This study observed that elderly women exhibited a tendency for higher personal anxiety and increased brain DC-potential indicators, with distinct energy cost patterns in different brain regions compared to elderly men.
36 citations
,
August 2011 in “Experimental Dermatology” In this study, researchers found no hypertrophy in axillary sweat glands of hyperhidrotic patients, with eccrine gland clear cells being the primary site of fluid transport and no evidence of apoeccrine glands.
June 2023 in “American Journal of Dermatopathology” In this study, central centrifugal cicatricial alopecia was the most common histopathologic diagnosis among Jamaican Afro-Caribbean patients with chronic hair loss, particularly affecting relatively young women.
12 citations
,
July 1957 in “Journal of Investigative Dermatology” This historical observation found that parathyroid extract treatment in newborn rats led to a condition resembling scleroderma, characterized by skin hardening, calcium deposition, and possible necrosis.
114 citations
,
February 2012 in “International Journal of Dermatology” This review examines the dermatologic effects of tobacco use and nicotine, noting potential benefits and drawbacks for various skin conditions, but reports no new clinical results.
38 citations
,
October 1988 in “Clinics in Dermatology” This article reviews the historical development of understanding the hair growth cycle, particularly anagen, catagen, and telogen phases, and reports no new clinical findings.
15 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.
7 citations
,
July 2020 in “Pigment cell & melanoma research” In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.
60 citations
,
September 1979 in “Fertility and sterility” This study found that spironolactone reduced testosterone production and urinary 17-ketosteroid excretion, leading to a decrease in hair growth rate and a change in hair texture in women.
23 citations
,
March 1994 in “Fertility and sterility” This study found that oral contraceptives effectively suppressed hyperandrogenemia in most patients with hyperandrogenic-insulin-resistant acanthosis nigricans syndrome, though GnRH-a therapy was beneficial for those not responding initially.
2 citations
,
December 2019 in “Journal of The European Academy of Dermatology and Venereology” This letter to the editor provides no abstract and reports no new research findings or results.
124 citations
,
March 2012 in “JAMA” This abstract discusses the unclear role of dihydrotestosterone (DHT) in postembryonic life in marsupials and possibly humans, reporting no new findings.
101 citations
,
October 2013 in “Journal of The Saudi Pharmaceutical Society” This study found that the nanostructured lipid carrier gel containing minoxidil showed good consistency and a prolonged drug release in vitro, suggesting potential for treating alopecia.
60 citations
,
September 2010 in “Journal of the American Academy of Dermatology” Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.
59 citations
,
October 2012 in “Pharmaceutical Research” This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.