Facile Water Mediated Synthesis of Finasteride Form-I, an Azaandrostane Steroid
January 2007
in “
Heterocyclic Communications
”
TLDR A simple and eco-friendly method was developed to make finasteride Form-I using water.
The document described a straightforward and efficient method for synthesizing finasteride Form-I from bis-finasteride tetrahydrofuran monohydrate solvate. This process utilized water as an eco-friendly solvent at room temperature, resulting in a good yield. The study provided Powder X-Ray diffraction data (PXRD) and Differential Scanning Calorimetric (DSC) data for the bis-finasteride tetrahydrofuran monohydrate solvate.
