TLDR A simple and eco-friendly method was developed to make finasteride Form-I using water.
The document described a straightforward and efficient method for synthesizing finasteride Form-I from bis-finasteride tetrahydrofuran monohydrate solvate. This process utilized water as an eco-friendly solvent at room temperature, resulting in a good yield. The study provided Powder X-Ray diffraction data (PXRD) and Differential Scanning Calorimetric (DSC) data for the bis-finasteride tetrahydrofuran monohydrate solvate.
17 citations
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January 1999 in “Journal of Molecular Structure” Finasteride's molecular and crystal structures help develop new drug formulations.
November 2020 in “Journal of The American Academy of Dermatology” Finasteride 1 mg every other month works as well as daily dose for hair loss maintenance.
June 2019 in “Journal of Drug Delivery and Therapeutics” Finasteride effectively treats hair loss and prostate issues with minimal side effects.
January 2013 in “China Medical Abstract of Dermatology” January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
12 citations
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October 2004 in “PubMed” Finasteride, especially in a 1mg dose, effectively slows hair loss and improves hair growth in Japanese men with male pattern hair loss.
10 citations
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June 2001 in “PubMed” Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.
3 citations
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October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
