44 citations
,
October 2017 in “British Journal of Dermatology” This review discusses the broadening scope of botulinum toxin applications beyond traditional uses, highlighting its effects on non-neuronal cells and potential in treating various dermatological conditions, without reporting new clinical findings.
44 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article updates a diagnostic tool (SALT II) for assessing hair loss by adding more precise measurements of scalp surface area, particularly useful for various types of alopecia.
25 citations
,
March 2019 in “Dermatologic therapy” This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.
25 citations
,
December 1995 in “Neurology” This study observed that in varicella, the varicella-zoster virus spreads to dermal endothelial cells before reaching keratinocytes, whereas in herpes zoster, it first involves cutaneous nerves and pilosebaceous units.
14 citations
,
September 2009 in “International Journal of Dermatology” This study found a potential link between staphylococcal carrier status and dermatitis cruris pustulosa et atrophicans, a chronic folliculitis primarily affecting the legs.
2 citations
,
July 2015 in “Archives of Dermatological Research” This study reports the first familial case of alopecia linked to a novel homozygous variant in the DSP gene, which did not coincide with heart abnormalities despite prior associations.
December 2025 in “Medical & Clinical Case Reports Journal” This article suggests that scalp erythrasma caused by Corynebacterium minutissimum may be underdiagnosed and that oral antibiotics used for other conditions could reduce its risk.
October 2023 in “Journal of the Endocrine Society” This study reported a rare case where a pheochromocytoma produced ACTH, leading to cyclic Cushing syndrome, and underscores the importance of considering this possibility in cases of ACTH-dependent hypercortisolism with an adrenal mass.
194 citations
,
May 2000 in “Journal of Investigative Dermatology” This study demonstrated that blocking the Sonic hedgehog signaling pathway in mice led to reversible inhibition of body coat hair morphogenesis, while whisker development was unaffected.
11 citations
,
October 2001 in “Tissue engineering” This study found that transplanted cultured epithelium from adult rat sole keratinocytes can respond to growth signals from dermal papillae and form follicular structures, especially with dermis support.
10 citations
,
September 2013 in “Nutrition” In this animal study, the ketogenic diet was associated with more severe biotin deficiency in biotin-deficient mice, suggesting that biotin supplementation is important when following this diet.
January 2023 in “Open veterinary journal” This study observed that applying a cream containing secretome from Bovine Umbilical Vein Endothelial Cells promoted healing and regeneration in burn wounds in rats, particularly at a 15% concentration.
108 citations
,
July 2002 in “Molecular and cellular biology” This study found that overexpressing Dsg3 in the suprabasal epidermis of transgenic mice resulted in flaking skin and abnormal hair growth, supporting Dsg3's role in regulating epidermal differentiation.
70 citations
,
May 2014 in “JAMA Dermatology” This study found that systematic review and protocol topics in the Cochrane Database for skin conditions are partly aligned with disease burden metrics, with some conditions overrepresented and others underrepresented compared to their disability-adjusted life years.
61 citations
,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that liposomes coated with cationic polymers, chitosan and Eudragit EPO, showed improved physicochemical stability and enhanced skin diffusion of aciclovir and minoxidil compared to uncoated liposomes.
55 citations
,
August 2015 in “AAPS PharmSciTech” This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.
47 citations
,
August 2016 in “Fitoterapia” This article reviews mechanisms by which herbal ingredients may stimulate or inhibit hair growth, and it reports no new clinical findings while suggesting potential for developing hair loss treatments.
38 citations
,
November 2016 in “Aaps Pharmscitech” This study found that the nanostructured lipid carrier formulation with a 70:30 solid to liquid lipid ratio significantly increased the dissolution rate, entrapment efficiency, and stability of spironolactone compared to its raw form.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” This study suggests that true binary and ternary inclusion complexes were formed between finasteride and 2-hydroxypropyl-ß-cyclodextrin, with or without the addition of specific polymers.
34 citations
,
October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
26 citations
,
March 2014 in “International journal of pharmaceutics” This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.
25 citations
,
June 2004 in “Journal of Investigative Dermatology” This study found that macrophage-stimulating protein (MSP) enhanced hair growth in both human hair follicles cultured in vitro and in mice through the promotion of anagen phase induction.
22 citations
,
January 2008 in “Physiological Research” This review discusses the role of steroid sulfatase in steroid hormone metabolism and highlights the need for more research on its expression and regulation, especially regarding hormone-dependent tumors.
21 citations
,
October 2009 in “Biochemical Engineering Journal” This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.
18 citations
,
August 2019 in “Drug Development and Industrial Pharmacy” This study concludes that phospholipid–polymer hybrid nanoparticles may be an effective delivery system for quercetin in treating androgenic alopecia by improving hair regrowth and preventing hair follicle cell apoptosis in rat models.
17 citations
,
July 2018 in “International Journal of Cosmetic Science” This study found that keratin-based particles were able to recover and enhance the mechanical properties and thermal stability of virgin and overbleached Asian hair, improving its strength and smoothness by around 40%, and demonstrated safety in human skin keratinocytes.
17 citations
,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.
15 citations
,
January 2022 in “Journal of Oleo Science” This study found that a phytosomal delivery system improved the bioavailability of Cuscuta reflexa extract compared to the plain extract, suggesting enhanced potential for this formulation.
15 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article discusses the potential of trichoscopy in diagnosing and treating dissecting cellulitis of the scalp and emphasizes the need for early diagnosis to prevent progression but reports no new clinical results.
13 citations
,
March 2019 in “Journal of cosmetic dermatology” This study found that thermal hair-straightening devices significantly damaged the cuticle and cortex of virgin Asian and Caucasian hair, with Asian hair experiencing more protein loss than Caucasian hair.