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Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

Adding a second method to PROTACs could improve cancer treatment.

Personalized treatments for hair loss are becoming more effective by using genetic information.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.

HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.

Scientists created a colored thread-like material containing a common hair loss treatment, which slowly releases the treatment over time, potentially offering an effective, neat, and visually appealing solution for hair loss.

A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.

Biologicals are increasingly used in medicine and cosmetics, especially for skin and hair treatments, but more research is needed.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Curcumin may help reverse aging by targeting specific genes.

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Finasteride effectively treats hair loss in Korean men for at least 5 years, with V type responding better.

D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

Sunflower oil was found to promote hair growth in mice with hormone-induced hair loss.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.

Histone modification is key in treating chronic inflammatory skin diseases.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Testosterone's muscle-building effects do not require its conversion to DHT.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride causes lasting fertility decrease in rats.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.