Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea Regia Fruits, in the Male Rat: A Comparison with Finasteride

December 2011 in “ Journal of Medicinal Food ”

Ariadne Gutiérrez Martínez, Balia Pardo, Rafael Gámez, Rosa Más, Miriam Noa, Gisela Marrero, Maikel Valle, Haydee García, Dayisell Curveco, Nilda Mendoza, E. Goicochea

D-004 lipid extract Roystonea regia finasteride androgen-dependent development anogenital distance retention of nipples prostate gland seminal vesicles dihydrotestosterone benign prostatic hyperplasia male pattern baldness Propecia DHT BPH

TLDR D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

The study investigated the effects of in utero exposure to D-004, a lipid extract from Roystonea regia fruits, on male rats and compared it to the effects of finasteride. The results showed that D-004 did not cause any alterations in androgen-dependent development, while exposure to finasteride during late gestation resulted in a permanent reduction in anogenital distance and retention of nipples in adult male rats. D-004 had similar effects to finasteride in reducing the weight of the prostate gland and seminal vesicles, as well as decreasing the levels of dihydrotestosterone. The study suggests that D-004 may have potential as a natural alternative to finasteride for the treatment of benign prostatic hyperplasia and male pattern baldness.

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Research cited in this study

4 / 4 results

research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia

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