56 citations
,
November 2012 in “Endocrinology” This study found that the absence of vitamin D receptor signaling in mice impairs the inflammatory response to skin injury, particularly affecting macrophage recruitment and granulation tissue formation.
44 citations
,
May 1998 in “PubMed” In this study, a specific retinoic acid receptor antagonist caused severe craniofacial anomalies in mouse fetuses when administered early in pregnancy, but not limb anomalies, highlighting developmental stage-specific roles of retinoic acid.
42 citations
,
February 2019 in “Circulation” This study observed that DNA damage response (DDR) plays a key role in pressure overload-induced cardiomyocyte hypertrophy, with disruption of the ATM kinase pathway potentially modulating this hypertrophy in mice.
25 citations
,
December 2008 in “Journal of Dermatological Case Reports” In this study, R-CSLM showed promise in evaluating hair shaft diseases by providing high-quality images of hair structures, although further development is necessary for follicle and perifollicular area analysis.
2 citations
,
January 2023 in “Pharmaceuticals” This study found that in male mice, microglial changes due to a Parkinson's-like lesion were influenced by sex hormones, with dutasteride treatment preventing some effects.
8 citations
,
August 2011 in “Journal of Medicinal Food” In this study, D-004 did not affect androgen-dependent development in rats exposed in utero, while finasteride caused significant changes in male offspring's androgen-dependent tissues.
October 2002 in “Dermatologic Surgery” This notice corrects an article on fluridil for androgenetic alopecia, indicating potential conflicts of interest due to the authors' patent holdings and funding source; it reports no new research findings.
5 citations
,
March 2012 in “Journal of Investigative Dermatology” In their mouse study, Oda et al. found that removing the MED1 gene in the skin led to hair loss and changes in epidermal cell differentiation, indicating MED1's significant role in these processes.
9 citations
,
August 2023 in “Sexual Medicine Reviews” This review reports that while intracavernosal platelet-rich plasma is considered safe for treating erectile dysfunction, its efficacy remains unclear due to variable clinical trial protocols.
3 citations
,
August 2022 in “Biochemical Genetics”
3 citations
,
May 2022 in “Experimental Dermatology” This review discusses the role of hair follicle stem cell metabolism, ageing, and microenvironment in hair growth disorders and compiles recent research on using stem cell-based regenerative medicine for treating alopecia, without reporting new clinical results.
November 2021 in “Plastic and Reconstructive Surgery” This supplement chronicles the 2020 Science of Aging Symposium, highlighting emerging discoveries in aging research, such as gene therapies and using AI for visualizing skin, without reporting new clinical results.
January 2026 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study reported high analytical performance of an RMP for DHT quantification, with the ability to differentiate between 5α-DHT and 5β-DHT isomers, making it suitable for routine assay standardization and clinical sample evaluation.
This review discusses finasteride's use in manipulating neuroactive steroid levels and its potential effects on behavior, reporting preclinical evidence and clinical observations but providing no new experimental results.
3 citations
,
January 2025 in “SAGE Open Medical Case Reports” In this case report, a 48-year-old woman with refractory discoid lupus erythematosus showed significant improvement, including hair regrowth, after treatment with deucravacitinib, suggesting its potential as an effective therapy for this condition.
April 2019 in “Journal of Investigative Dermatology” The study suggests that variability in platelet-derived growth factors in PRP is influenced by both patient-to-patient differences and the devices used for PRP preparation, contributing to inconsistent clinical outcomes in hair loss treatments.
19 citations
,
December 2008 in “Arthritis Care & Research” This study found that the decision board is a reliable and valid tool for assessing treatment preferences in systemic lupus erythematosus patients, who tended to favor oral medication due to concerns about side effects.
3 citations
,
June 2018 in “Internal Medicine” In this study, a patient with Cronkhite-Canada syndrome complicated by severe sepsis and disseminated intravascular coagulation was successfully treated using combined therapies, including recombinant human soluble thrombomodulin, despite the absence of a standard treatment regimen for CCS.
1 citations
,
January 2020 in “Indian journal of dermatology, venereology, and leprology” This study found that the expression of CD117 and platelet-derived growth factor receptor α differs in alopecia areata tissue compared to normal controls, with platelet-derived growth factor receptor α correlating with disease severity.
54 citations
,
January 2007 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that hair follicle homeostasis in mice requires vitamin D receptor expression in keratinocytes, independent of its ligand activation.
144 citations
,
December 2004 in “Molecular Endocrinology” This study found that the effects of the vitamin D receptor on hair follicle cycling in mice are independent of its ability to bind a hormone, with specific domain mutations influencing hair regrowth outcomes.
July 2025 in “SVU-International Journal of Medical Sciences” This case report presents the dental challenges faced by a child with vitamin D-dependent rickets type II, including early onset rickets, alopecia, and specific dental abnormalities, emphasizing the need for comprehensive, multidisciplinary management.
20 citations
,
December 2013 in “PTR. Phytotherapy research/Phytotherapy research” This study found that ginsenoside Rg3 up-regulates vascular endothelial growth factor expression in human dermal papilla cells and mouse hair follicles, suggesting its potential role in promoting hair growth.
4 citations
,
February 2024 in “Scientific Reports” This study found that Platelet Rich Plasma is effective as a direct pulp capping agent, comparable to Mineral Trioxide Aggregate, but with potentially better cellular dentinogenic responses and homogenous tissue formation in dogs.
25 citations
,
November 2005 in “PubMed” This study found that finasteride altered androgen receptor expression in the rat epididymis without affecting the morphology of epididymal epithelium, suggesting a change in hormonal status.
5 citations
,
January 2001 in “Advances in protein chemistry” This chapter reviews recent advances in 5α-reductase inhibitors for treating disorders mediated by dihydrotestosterone and reports no new clinical findings.
February 2016 in “Journal of Allergy and Clinical Immunology” This report highlights a case of disseminated and recurrent infundibulofolliculitis in a 45-year-old African American male and underscores the importance of performing a skin biopsy for diagnosis.
June 2023 in “The journal of sexual medicine” This case report describes a 10-year multidisciplinary treatment of a transgender woman in Slovenia, reporting a successful medical and social transition with stable emotional health, abstinence from alcohol, and no regrets following her transition.
4 citations
,
February 2024 in “The Journal of Urology” This study reports that adding androgen deprivation therapy to salvage radiation therapy for patients with non-metastatic biochemical recurrence of prostate cancer after radical prostatectomy improves progression-free survival, particularly in those with higher post-prostatectomy PSA levels.
December 2023 in “Alzheimer's & Dementia” In this study, chronic exposure to finasteride induced metabolic disturbances and depression-like behaviors in young male rats, similar to those caused by obesity, but did not worsen anxiety or depression in obese rats.