July 2026 in “Theranostics” This study developed a novel ferritin-based delivery system (LR@Fn) that effectively co-delivers RG108 and LLY283 for hearing loss treatment in animal models, reducing hair cell loss and synaptic damage more effectively than dexamethasone.
19 citations
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July 2005 in “Steroids” In this study, researchers developed a sensitive LC–MS–MS assay to measure 3α-androstanediol levels in rat plasma and observed that testosterone raises these levels via a 5α-reductase pathway.
59 citations
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April 2016 in “Cell Reports” This study demonstrated that EdnrB signaling promotes melanocyte stem cell proliferation and differentiation, enhancing hair and epidermal melanocyte regeneration, especially under conditions of active Wnt signaling.
4 citations
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January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.
October 2024 in “Frontiers in Pharmacology” The correction does not change the conclusion that 2-deoxy-D-ribose helps hair regrowth.
January 2004 in “Data Archiving and Networked Services (DANS)” This study found that finasteride blocked the progesterone-induced increase in spike-wave discharges in rats, suggesting that this effect of progesterone is mediated by its metabolite allopregnanolone.
January 2011 in “Medical Recapitulate” This article reviews the role of 5α-reductase in androgen-related diseases like acne and androgenetic alopecia and reports no new clinical results, emphasizing the importance of studying the enzyme.
This study found that a mesenchymal stromal cell-derived regenerative extracellular matrix (rECM) significantly accelerated wound closure and improved healing in diabetic mice, also enhancing nerve and blood vessel formation compared to controls.
January 2026 in “Queensland University of Technology” This thesis reviews current therapeutic approaches for ARFID and provides preliminary insights into enhancing treatment and care in Australia, including an evaluation of a pilot dietetic-led cognitive-behavioral therapy intervention.
October 2021 in “Revista Medicina Cutánea Ibero-Latino-Americana” This case report describes a patient who developed PRIDE syndrome-associated skin issues, including a pruritic papulopustular rash and alopecia, after starting treatment with the EGFR inhibitor erlotinib.
This study found that finasteride treatment in male rats has lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation, and gut microbiota composition even one month after discontinuation.
February 2024 in “Indian Journal of Postgraduate Dermatology” Senior residency helps dermatology graduates develop skills and plan their careers.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
January 2022 in “Chemistry: A European Journal” This study found that synchrotron radiation ECD imaging provides new insights into solid-state Finasteride by highlighting the significant role of anisotropy in local domains for chiroptical measurements.
December 2010 in “OhioLink ETD Center (Ohio Library and Information Network)” In this study, total Sry transcript expression in various rat tissues was linked to Acsl3 expression, suggesting that Sry may play a role in regulating fatty acid metabolism.
August 2024 in “British Journal of Dermatology” The trial is ongoing, but researchers are evaluating the efficacy and safety of REZPEG, a potential new therapy for severe alopecia areata, which selectively expands regulatory T cells.
May 1999 in “Hair transplant forum international” This letter challenges Dr. Rogers' comments about the British Association of Hair Restoration Surgeons, highlighting discrepancies between his statements and the facts; it provides no new research results.
38 citations
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October 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the clinical and molecular history of 5-alpha reductase deficiency, highlighting its role in male sexual differentiation and potential therapeutic applications, but reports no new research outcomes.
January 2013 in “International journal of trichology” Vitamin D3 and its receptor are important for hair growth, and understanding receptors could help treat hair graying and skin cancer.
7 citations
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April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
January 2026 in “American Journal of Medical Genetics Part A” The researchers reported two brothers with a new variant of X-linked trichothiodystrophy associated with an RNF113A gene mutation, highlighting features such as intellectual disability and growth failure, but without previously reported endocrinological or genital abnormalities, underlining the importance of genetic counseling for such variants.
May 2021 in “Journal of Advances in Internal Medicine” This case report describes a 13-year-old with DSD raised as female, exhibiting hoarseness and clitoral enlargement, with hormonal assessments not indicating common related deficiencies.
4 citations
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October 2023 in “Journal of Medicine and Life” In this study, UDCA treatment reduced inflammation, oxidative stress, and cartilage damage in rats with experimentally induced rheumatoid arthritis, suggesting potential anti-rheumatoid arthritis properties.
158 citations
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August 2011 in “Reviews in endocrine and metabolic disorders” This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.
126 citations
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October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.