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Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.

A group has developed therapies that show promise for treating cancer and various other conditions.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Scientists successfully edited a goat's genes to grow more and longer cashmere hair.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.

Gender-specific analysis could improve treatment for childhood systemic lupus erythematosus.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Adding a second method to PROTACs could improve cancer treatment.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Herpes zoster infection can cause permanent hair color change in the affected area.

Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

New drugs for rheumatoid arthritis show improvement but have side effects and are not a cure.

The skin microbiome helps heal wounds and can be targeted to improve healing.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.