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Melatonin may protect hair follicle stem cells from damage caused by chemotherapy.

Melatonin may help prevent hair loss caused by the chemotherapy drug paclitaxel.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

More precise, personalized therapies are needed for autoimmune diseases.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Polyamines help fix DNA damage accurately in cells.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Lupus can look like hair loss from alopecia areata but needs different treatment.

A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.

Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.

Careful management of blood thinners is crucial for lupus patients with APS.