22 citations
,
October 2020 in “Anais Brasileiros de Dermatologia” This consensus concluded that oral isotretinoin is highly effective for treating acne and some off-label conditions, with common adverse events being manageable and rare serious risks not contraindicating use.
20 citations
,
April 2021 in “Journal of Womens Health” This guideline provides evidence-based recommendations for prescribing testosterone therapy to women with hypoactive sexual desire disorder, noting a moderate therapeutic benefit but highlighting limited data and regulatory challenges.
20 citations
,
June 2020 in “Journal of Advanced Research” This study found that high-dose vitamin A and E supplementation with zinc may improve glycemic control and beta-cell function in patients with type 2 diabetes, compared to no supplements.
20 citations
,
February 2017 in “International Journal of Dermatology” This review highlights recent findings on blood-derived autologous therapies for skin repair and wound healing but presents no new clinical results, emphasizing future challenges and prospects in regenerative dermatology.
17 citations
,
May 2018 in “PeerJ” This study found that VB-1, a vitexin compound, may promote hair follicle growth by enhancing Wnt/β-catenin signaling in human dermal papilla cells in vitro.
17 citations
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June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, FCE 28260 showed greater potency than finasteride in inhibiting 5α-reductase enzymes and reducing prostate DHT levels in rats.
16 citations
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June 2021 in “Journal of Dermatological Treatment” This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.
16 citations
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March 2009 in “Skin Pharmacology and Physiology” This study found that the penetration enhancer SEPA™ significantly increased both the speed and amount of hair growth from minoxidil in balding stumptail macaques compared to Rogaine®.
14 citations
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June 2009 in “Journal of veterinary internal medicine” This study describes presumed albendazole toxicosis in alpacas, suggesting that repeated doses as low as 19 mg/kg can lead to severe neutropenia, enteropathy, and potentially death in this species.
13 citations
,
November 2024 in “Anais Brasileiros de Dermatologia” This abstract highlights the potential applications of exosomes in dermatology, including scar treatment and hair regeneration, but notes that further clinical studies are needed to confirm their safety and efficacy and address regulatory challenges.
13 citations
,
July 2012 in “Dermatologic Surgery” Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.
13 citations
,
October 2010 in “Pharmacogenomics” This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.
12 citations
,
January 2011 in “Dermatologic Surgery” This entry contains only a placeholder abstract with no research findings described or summarized.
11 citations
,
January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
11 citations
,
February 1986 in “Archives of Dermatology” This study found that 5% topical minoxidil solution led to better hair regrowth response and quality in severe alopecia areata compared to 1% solution, despite regrowth often being cosmetically unacceptable.
10 citations
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July 2016 in “Clinical and translational science” In this study, sorafenib's common adverse events, like a hand-foot syndrome and diarrhea, were observed in distinct temporal and tissue distribution patterns, revealing new relationships among effects.
10 citations
,
February 2016 in “The Journal for Nurse Practitioners” This article discusses the basic care and issues primary care providers should consider when treating transgender patients, but it reports no new clinical results.
10 citations
,
October 2010 in “International Journal of Andrology” In this study, co-administration of finasteride with oral testosterone undecanoate in young men with induced hypogonadism had no significant effect on serum testosterone or dihydrotestosterone levels, likely due to TU's unique absorption route.
9 citations
,
August 2023 in “Sexual Medicine Reviews” This review reports that while intracavernosal platelet-rich plasma is considered safe for treating erectile dysfunction, its efficacy remains unclear due to variable clinical trial protocols.
9 citations
,
November 2017 in “Dermatologic Clinics” This article reviews botulinum toxin use in men, focusing on anatomical and treatment differences, with no new clinical results.
8 citations
,
January 2025 in “JADA Foundational Science” This review discusses the state-of-the-art in photobiomodulation therapy for oral and dental applications and emphasizes the need for education, training, and addressing logistical issues for its routine use.
8 citations
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June 2013 in “Journal of bone and joint surgery. American volume/The Journal of bone and joint surgery. American volume” This commentary highlights that while platelet-rich plasma (PRP) is widely used in orthopaedic and cosmetic treatments, its effectiveness is questionable and varies with different compositions and applications.
7 citations
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April 2023 in “Frontiers in Surgery” This study found that a single dose of 1 mg/kg dexamethasone promoted wound healing in septic mice but delayed it in normal mice.
7 citations
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May 2022 in “International Journal of Environmental Research and Public Health” This study found that isotretinoin therapy for acne vulgaris typically causes mild mucocutaneous adverse events, which are reversible and vary individually.
This article discusses the features and increasing prevalence of frontal fibrosing alopecia, a type of scarring hair loss, and reports no new clinical results.
7 citations
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December 2011 in “InTech eBooks” This review discusses current and evolving treatment strategies for congenital adrenal hyperplasia in adolescents and adults, focusing on glucocorticoid and mineralocorticoid therapy and the management of insulin resistance, without reporting new clinical results.
7 citations
,
December 1971 in “Calcified Tissue Research” Hair follicles in injured skin can quickly accumulate minerals, especially calcium and phosphorus.
6 citations
,
December 2023 in “Journal of Clinical Medicine” This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.
6 citations
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November 2023 in “Clinical Pharmacokinetics” This research discusses the parallel clinical development of ritlecitinib, an oral Janus kinase 3/tyrosine kinase inhibitor, for treating conditions such as alopecia areata, vitiligo, ulcerative colitis, Crohn's disease, and rheumatoid arthritis. Results are not reported in the abstract.
6 citations
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January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topically applied liposomal spherical nucleic acids targeting the IL-17 receptor could effectively reduce psoriasis severity in preclinical models.