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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Muscles can make their own androgens, which may help muscle growth.

TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Different light affects cell functions and can help treat skin conditions.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

Vitamin D receptor helps control hair growth genes in skin cells.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Vitamin D receptor is crucial for skin wound healing.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.