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This study found that nanostructured lipid carriers enabled effective follicular delivery and accumulation of anti-hair loss drugs like dutasteride in mice, suggesting potential for reduced dosage frequency.

This study found that a low-dose oral contraceptive containing dienogest provides effective contraception, improves cycle stability, and may reduce excessive scalp and skin oiliness, with high user satisfaction.

This study evaluated Finasteride-loaded nanostructured lipid carriers for topical use in treating androgenetic alopecia and found that these carriers offer sustained drug release and may reduce systemic side effects compared to oral administration.

This publication discusses the political rationale behind the French regulator ANSM's decision to withdraw Diane®-35 from the market, in response to health concerns associated with third-generation oral contraceptives.

This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.

A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

This study developed a nanostructured lipid carrier for 17-α-estradiol that showed stable physicochemical properties and improved targeting to hair follicles in alopecia treatment.

This study reported that Diane-35 treatment over 6-9 months reduced hair loss, hair thinning, and seborrhoea in women with androgenetic alopecia.

This study suggests that Aldactone may be more effective than Diane in reducing hair growth, despite having minimal impact on hormone levels.

This study found that dutasteride-loaded nanostructured lipid carriers coated with a stearic acid-chitosan oligomer are stable, less cytotoxic, and suitable for topical delivery to promote hair growth.

This study suggests that using nanostructured lipid carriers may improve the targeting of 17-α-estradiol in treating alopecia by improving skin penetration and stability.

This study explored a new dutasteride nanocarrier for alopecia therapy, concluding that ingredient concentration is key to achieving the optimal particle size, stability, and skin permeation for extended drug release.

Nanocarriers with spironolactone and 2-deoxy-D-ribose may improve hair loss treatment by targeting hair follicles directly.

In this study, Diane was reported to effectively treat acne, seborrhoea, androgenic alopecia, and mild hirsutism in hirsute women, with its effectiveness influenced by the severity and duration of the condition.

This study formulated and characterized a dutasteride-loaded nanocrystalline suspension for long-acting parenteral delivery, finding that it provided sustained drug release in rats with a significant reduction in local inflammation over 28 days following intramuscular injection.

This study developed nanostructured lipid carriers for finasteride that demonstrated high encapsulation efficiency and reduced cytotoxicity, suggesting potential as a topical treatment for androgenetic alopecia.

In this study, the researchers compared the pharmacokinetics and tissue distribution of dihydroartemisinin in nanostructured lipid carriers versus in solution, finding longer mean residence times and variable organ accumulation with the nanostructured lipid carriers.

This meta-analysis found that while both Dienogest and GnRH analogues effectively managed endometriosis-related pain, Dienogest reduced recurrence rates and hot flushes but increased irregular bleeding, making it a safer option due to fewer side effects.

This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.

In this study, researchers developed isotretinoin-loaded Delonix polymeric nanoparticles that target hair follicles and found they effectively sustained drug release, reduced IL-6 production in vitro without inhibiting P. acnes, and may prevent isotretinoin-related skin irritation in vivo in Wistar rats.

This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.

Combining topical dutasteride with microneedling is more effective for hair growth than microneedling alone.

This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.

This review explores the potential, challenges, and recent advancements of dissolving microneedles in drug delivery, summarizing their varied applications and current limitations without providing new clinical results.

This study observed a strong overall reduction in the use of CPA/EE in the Netherlands, despite similar proportions of users with acne or other hyperandrogenic conditions before and after the referral procedure.

This letter highlights that levonorgestrel intrauterine devices may lead to fewer systemic side effects, like acne, compared to its oral administration due to lower systemic levels of progestogens.

This study found that the LightSheer Diode EP Laser System significantly reduced hair growth among women with hirsutism, with side effects disappearing within three days and no long-term skin pigmentation issues observed.

The study found that cyproterone acetate-loaded nanostructured lipid carriers, particularly those with a 300 nm diameter, improved skin penetration and targeted hair follicles more effectively than free cyproterone acetate.

This study reported that an injectable hydrogel based on platelet-rich plasma and laponite improved wound healing in diabetic and normal rats by enhancing angiogenesis and macrophage polarization.