19 citations
,
January 2022 in “Journal of Nanomaterials” This study concluded that an adapalene nanohydrogel containing Tween-80 could be a promising and stable topical treatment option for acne vulgaris due to enhanced skin permeability and stability compared to other formulations.
36 citations
,
April 2022 in “Nutrients” This review discusses the potential of Lansium domesticum as a herbal medicine, summarizing its traditional uses, nutritional value, bioactivities, and related nanoparticles and pharmaceutical formulations, but reports no new experimental results.
6 citations
,
November 2017 in “Skin appendage disorders” This study found that a new topical botanical lotion significantly increased hair density and improved quality of life in women with androgenetic alopecia over 24 weeks.
2 citations
,
March 1976 in “PubMed” In this study, Neogynon was found to be 100% effective as a contraceptive, with no observed failures in 3129 cycles among 184 women, while side effects included changes in endometrial patterns and some central nervous system effects.
17 citations
,
June 2017 in “Journal of pharmaceutical sciences” This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.
This review discusses the potential of using sustained release systems to increase the effectiveness and reduce side effects of 17-alpha-estradiol in alopecia treatment and reports no clinical results.
38 citations
,
November 2016 in “Aaps Pharmscitech” This study found that the nanostructured lipid carrier formulation with a 70:30 solid to liquid lipid ratio significantly increased the dissolution rate, entrapment efficiency, and stability of spironolactone compared to its raw form.
12 citations
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July 2020 in “International Journal of Pharmaceutics” This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.
3 citations
,
May 2023 in “PLoS ONE” This study found that while both professional and home-use lasers effectively reduced axillary hair, the professional Diode laser was significantly more effective, achieving 85-88% reduction compared to 46-52% with the home-use laser, which still offers some safety for users.
8 citations
,
September 2023 in “Advanced Pharmaceutical Bulletin” In a double-blind clinical trial, this study found that a gel containing chitosan-coated spironolactone nanoparticles effectively reduced acne lesions over 8 weeks without adverse skin effects, suggesting potential for enhanced acne treatment through targeted skin delivery.
July 2026 in “Drug Delivery Letters” This review discusses the potential of nanostructured lipid carriers to improve herbal treatments for alopecia and reports no new clinical results, highlighting the need for further clinical trials and safety data.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports the discovery of LX-38, a novel non-steroidal drug candidate that may offer safer treatment for conditions like Benign Prostatic Hyperplasia by avoiding hormonal side effects associated with current therapies.
18 citations
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September 2021 in “Colloids and surfaces. B, Biointerfaces” This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.
January 2017 in “The American Pharmacists Association eBooks” January 2017 in “The American Pharmacists Association eBooks” July 2026 in “Journal of Drug Delivery Science and Technology”
This study assessed the effects of a formulation containing millet extract, wheat germ oil, L-cystine, and calcium pantothenate on women with telogen effluvium using Digital Phototrichogram, but it reports no new results.
14 citations
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July 2021 in “Journal of the American Academy of Dermatology” Topical dapsone gel reduced flare-ups in folliculitis decalvans without side effects.
53 citations
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November 2014 in “International Journal of Oncology” This study found that wedelolactone, a natural compound from plants, inhibited breast cancer-mediated osteoclast differentiation and activity in vitro, suggesting its potential as a therapy for bone destruction in breast cancer bone metastasis.
December 2025 in “Sensors” In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.
January 2020 in “International Journal of Research in Pharmacy and Chemistry” This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.
December 2023 in “Reactions weekly” December 2023 in “Reactions weekly” September 2013 in “Reactions weekly”
24 citations
,
October 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that the LH response to nafarelin effectively distinguished gonadotropin deficiency from constitutional delay of puberty, performing comparably to the sleep test and offering certain advantages.
July 2022 in “International Journal of Applied Pharmaceutics” This study concluded that the optimized caffeine-loaded nanostructured lipid carriers improved hair growth by enhancing permeation through skin layers more effectively than an existing market formula.
This study observed that women using combined oral contraceptives experienced more nausea, vomiting, and hair loss, while those on Depo-Provera were more likely to gain weight.
64 citations
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June 2009 in “Journal of The American Academy of Dermatology” This article discusses frontal fibrosing alopecia, noting potential connections to lichen planopilaris, but reports no new clinical findings.
January 2026 in “Journal of Sexual and Mental Health” This study reports that two oral hormonal agents, dimethandrolone undecanoate and 11β-methylnortestosterone dodecylcarbonate, may effectively suppress hormones to contraceptive levels in men with mild side effects, though longer-term trials are required to confirm their safety and efficacy.
January 2026 in “Elsevier eBooks”