106 citations
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January 2016 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.
105 citations
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April 2017 in “International Journal of Nanomedicine” In this study, ethosomes were found to improve the skin penetration of a model lipophilic drug more effectively than liposomes or hydroethanolic solutions, suggesting a unique mechanism involving the breakdown of vesicles in the skin.
March 2021 in “International journal for research in applied science and engineering technology” In this study, researchers explored the use of natural herbal hair dyes made from tannin-producing plants like henna and pomegranate, reporting that these dyes can permanently color hair without causing damage or irritation, unlike synthetic dyes.
This study found that papaya seed extract gel accelerated hair length growth in rabbits, with the most effective concentration being 15%, though it did not significantly affect hair mass.
This study found that bitter melon leaf extract, particularly at a 10% concentration, promoted hair growth in male rabbits, outperforming the effect of a 2% minoxidil solution.
July 2025 in “Biotechnology and Bioprocess Engineering” Spirulina extract may effectively promote hair growth and reduce inflammation, offering a natural alternative for hair loss treatment.
December 2024 in “Journal of Health and Beauty” This study found that the Dongeui Hot Spring Water complex (Dongui Hot Spring Water CPX), containing sea slug extract and panthenol, demonstrated higher antioxidant activity and cell proliferation, suggesting potential benefits for preventing hair loss and improving scalp health.
December 2024 in “Journal of Health and Beauty” In laboratory conditions, this study found that the Dongeui Hot Spring Water Complex, containing sea slug extract, demonstrated enhanced antioxidant activity and promoted hair papilla cell proliferation compared to a control, suggesting potential benefits for scalp health and hair loss prevention.
January 2017 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” In this study, administering varying doses of Hibiscus rosa-sinensis leaf water extract to BALB/c mice for 28 days did not result in significant changes in haematological parameters, body weight, or food consumption, suggesting no noticeable toxicity effects in the tested conditions.
4 citations
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January 2010 in “Laboratory Animal Research” This study found that Na2SiO3 accelerated hair regrowth in mice, indicating potential for treating alopecia, though it did not significantly alter enzyme activity compared to distilled water.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers observed that rosemary plant extracts (essential oil, hydrolate, and alcoholic extract) promoted hair growth in male mice more than a distilled water control and even performed better than 5% minoxidil over five weeks.
In this study, rosemary extracts (essential oil, hydrolate, and alcoholic extract) significantly stimulated hair growth in male mice compared to distilled water and even to commercial minoxidil, with rosemary groups showing statistically superior results on hair length.
January 2022 in “Buletin penelitian tanaman rempah dan obat/Bulletin komunikasi penelitian tanaman rempah dan obat” This study observed that a hair tonic containing 3% ethanolic extract of bidara leaves stimulated rabbit hair growth more effectively over 28 days than both distilled water and 2% minoxidil, attributing this effect to the extract's anti-inflammatory and antioxidant properties.
9 citations
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January 2014 in “DARU Journal of Pharmaceutical Sciences” This study found that Cuscuta reflexa extracts promoted hair regrowth and follicular proliferation in cyclophosphamide-induced hair loss in male rats.
3 citations
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December 2020 in “Pharmaceutical Sciences and Research” This study found that using 70% ethanol as a solvent for extracting unsoaked Leucaena leucocephala seeds produces a high extract yield while managing mimosine levels, indicating potential for nutraceutical use.
2 citations
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February 2022 in “Preprints.org” This study found that fermented red ginseng marc alleviated skin lesions, reduced inflammation, and demonstrated antioxidant effects in an AD-like mouse model, suggesting potential therapeutic applications for atopic dermatitis.
1 citations
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November 2022 in “International Journal of Molecular Sciences” This study observed that Kelulut honey effectively normalized the expression of certain sex steroid receptors in PCOS-induced rats, similar to metformin and clomiphene.
1 citations
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April 2021 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” In this study, researchers found that using 0.75% aspartic acid as an intermediate agent for a permanent wave improved wave formation and retention compared to a control in virgin hair, also reducing cuticle damage and maintaining tensile strength.
March 2026 in “The Korean Society for Veterinary Nursing” In this study, Eremochloa ophiuroides-derived fractions were found to significantly promote hair regrowth in a mouse model, demonstrating effects comparable to minoxidil and suggesting potential as natural hair growth agents through modulation of follicular activation markers and growth-regulatory factors.
August 2024 in “Siberian Journal of Life Sciences and Agriculture” In this study, researchers found that both oral and percutaneous applications of melatonin and lyotritone in laboratory rats enhanced hair quality and growth rate compared to a control group, which showed slower hair growth and lower hair quality.
May 2024 in “Research Journal of Pharmacy and Technology” This study introduced new spectrophotometric methods to estimate Minoxidil in pharmaceutical forms, demonstrating its linearity across various buffers and solvents, and found these methods to be simple, economical, and effective according to ICH guidelines.
September 2023 in “Tạp chí Y Dược học Cần Thơ” In this study on diabetic mice, researchers demonstrated that onion extract significantly lowered blood glucose levels at doses of 500mg/kg and 1,000mg/kg, showing comparable effectiveness to the diabetes medication metformin.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.
December 2020 in “Nigerian journal of animal production” This study found that dexamethasone may induce diabetes in albino rats and Annona muricata methanolic bark extract resulted in significantly reduced blood sugar levels in dexamethasone-induced diabetic rats.
June 2017 in “Jurnal Biomedik : JBM” This study found that oral broiler meat extract increased body weight, visceral fat mass, and the number of hair follicles in young male Wistar rats.
March 2009 in “Journal of Biomedical Research” In this study, herbal extract mixtures applied to mice accelerated hair regrowth compared to a control group, suggesting potential hair-growing properties.
69 citations
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February 1987 in “Archives of Dermatology” This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.
15 citations
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May 2006 in “Brain & development” The authors concluded that administering biotin may help prevent alopecia caused by reduced biotinidase activity during valproic acid therapy in rats.
15 citations
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February 1987 in “Archives of Dermatology” In this case report, a 23-year-old man with alopecia universalis applied topical cyclosporine for several months, resulting in noticeable hair regrowth.
13 citations
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January 1988 in “Contact Dermatitis” This article has no abstract and reports no new findings, focusing instead on allergic contact dermatitis reactions to topical Minoxidil documented in previous studies.