Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.

This review explores how microneedles can improve the delivery of dermatological treatments by bypassing the skin's outer barrier, discussing their potential use in managing skin diseases, cosmetic applications, and challenges related to clinical adoption.

This study examines the role of nanotechnology in cosmetics, highlighting its benefits in improving ingredient solubility and stability, but also noting challenges such as cost, shelf life, and safety concerns, along with regulatory complexities, particularly in harmonizing global legislation.

This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.

This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.

This review summarizes the therapeutic potential and development of engineered extracellular vesicles for tissue repair and regenerative medicine, reporting no new clinical findings.

This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.

This study found that nanoemulsion-based formulations, such as nanoemulgel and NFs, might serve as promising topical delivery systems for treating inflammatory diseases, potentially offering an alternative to traditional nonsteroidal anti-inflammatory drugs, which are associated with adverse effects.

This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.

This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.

This review discusses the unique advantages and challenges of microneedle arrays for vaccine and immunotherapy delivery but reports no new clinical results.

This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.

This review examines the promising role of nanocarriers, specifically liposomes and ethosomes, in enhancing transdermal drug delivery for skin diseases. Ethosomes, highlighted for their ability to penetrate deeper skin layers, show potential for more effective treatments but require further clinical investigation.

This study reported that a newly formulated Curcumin-loaded proniosome, named F5, exhibited enhanced antiviral efficacy, stability, and safety when compared to Curcumin alone, and improved the therapeutic performance of Acyclovir by reducing its effective dose against Herpes simplex virus.

This review discusses the use of nanocarrier technology in functional cosmetics to enhance skin penetration, increase ingredient stability, and allow codelivery of active ingredients, without reporting new clinical results.

This review discusses the types, causes, and treatments for skin pigmentation disorders, examining clinically tested options including 25 plants, four marine species, and 17 medications.

This overview outlines the latest advancements and challenges in developing three-dimensional scaffolds for biomanufacturing cultured meat, focusing on organizing muscle stem cells to better mimic the structure of traditional meat. Results are not reported in the abstract.

This article provides an overview of microneedle technology for transcutaneous drug delivery, discussing microneedle designs, materials, and activation methods that enhance drug stability and regulated release, and outlines considerations for their successful clinical implementation, such as biocompatibility and production cost.

This study concluded that leucocyte-rich PRP has a continuous stimulatory effect on human fibroblast cells, enhancing their proliferation, migration, and impacting gene expression of the extracellular matrix and adhesion molecules.

The researchers suggest that combining microneedle technology with nanocarriers could enhance drug delivery systems for treating central neurological diseases due to nanoparticles' ability to prolong blood circulation time and improve brain targeting.

This review discusses the potential of nanoparticles to modify angiogenesis processes for therapeutic applications and reports no new clinical results, highlighting challenges and future prospects in treating angiogenesis-related diseases.

This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.

This review reports that cubosomes, used as drug nanocarriers in topical treatments, offer potential benefits for managing skin and eye diseases by improving bioadhesion, retention, and sustained release compared to conventional formulations, but also face manufacturing and biological challenges for effective clinical outcomes.

This study describes the development of microneedle array patches for finasteride that released the drug over 7 to 14 days in vitro, suggesting a potential alternative to oral treatments for long-term management of benign prostatic hyperplasia and androgenic alopecia.

This study found that minoxidil solubilized in gelatin-containing microemulsions resulted in over 5% of the drug remaining in porcine skin, significantly more than the reference gel.

This review examines the major biomaterials used in skin wound healing and evaluates experimental therapies but reports no new research findings.

This review discusses the potential of fibrinolytic enzymes from various sources, especially fermented foods, for their therapeutic use in cardiovascular diseases and emphasizes the need for further research on those from non-Asian regions to optimize discovery and application.

This review focuses on recent advances in smart responsive polymer microneedles, which offer precise, on-demand drug delivery triggered by external or physiological stimuli, highlighting significant research implications for transdermal drug administration according to this source.

This review explores the similarities between wound healing, palatogenesis, and orofacial clefting, suggesting these processes share common pathways and genetic regulatory mechanisms, but reports no new experimental results.

This study found that azelaic acid entrapped in transethosomes exhibited enhanced antidermatophyte activity and improved treatment outcomes in guinea pig models of dermatophytosis compared to free azelaic acid.