Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that shikimic acid- and maleate-based hair repair agents modified the structure of hair fibers, though they did not increase disulfide bridge content in the hair cortex.

In this study, cryopreserved mouse whisker hair follicles were shown to maintain their hair growth potential and functional recovery, with DMSO being more effective than glycerol for cryopreservation.

This case report indicates that contact dermatitis on the face can result from using a bleaching ointment containing ammonium bisulfite during hair-dyeing.

Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.

Niosomes are a promising and effective way to deliver drugs through the skin.

This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.

This article reviews small animal experiments reported from 1932 to 1952 in two dermatology journals and notes the contributions of Farris's book on laboratory animal care.

This chapter describes the functions and purposes of hair care cosmetics, including shampoos, hair growth promoters, and grooming products, without reporting new experimental findings.

This chapter covers various dermatological drugs, cosmetics, and topical agents, focusing on the properties and uses of propolis, but does not present new clinical findings.

This chapter reviews dermatological drugs and cosmetics, identifying common allergens and preservatives linked to contact dermatitis without reporting new clinical results.

This study suggests that ethylene and lignoceric acid (C24:0) may promote cotton fiber and Arabidopsis root hair growth by activating the pectin biosynthesis network.

This study found that human hair follicles express ATP-sensitive potassium channels, suggesting that minoxidil acts on these channels and that drugs targeting them may treat hair disorders.

This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.

This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.

This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.

In this study, researchers measured the solubility of Minoxidil in supercritical CO₂ under various temperature and pressure conditions and created models to estimate solubility based on different predictive approaches.

This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.

This review highlights that although mangiferin, a polyphenol from the mango tree, faces challenges like low solubility and bioavailability, delivery vehicles such as nanoparticles and complexes have the potential to enhance its therapeutic effectiveness in treating various diseases.

The researchers reported creating a Human Hair Atlas that maps over 1200 molecular species in hair, revealing up to 50% variation in metabolite and lipid levels along the hair's length, and identified 122 exposome-related compounds from personal care products.

In this study, biotin supplementation was found to significantly increase wool follicle viability and metabolic activity in vitro, with the highest effects observed at 0.5 mg L⁻¹ concentration.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

This review summarizes the association between 5-alpha reductase inhibitors and depression, discussing potential mechanisms such as neuroactive steroid alterations and neuroinflammation, but reports no new clinical results.

This study explored the creation of 3D-printed baricitinib pills using polylactic acid and found that the doughnut-shaped tablets increased surface area and drug release, with 59% released from the higher concentration pill over 24 hours.

This study found that Peperomia pellucida, a plant traditionally consumed in some countries, contains various antioxidants and extends lifespan under oxidative stress in Drosophila, with no observed toxicity in mice, supporting its potential safety and use in foods and pharmaceuticals.

This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.

In this study, nitrogen starvation in Chlorella sp. FC2 IITG led to increased lipid accumulation by altering the expression of enzymes involved in various metabolic pathways, suggesting potential for genetic engineering of microalgae.

This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.

This study found that β-sitosterol, a brain-penetrable phytosterol, reduced melanoma cell growth and brain metastasis formation by interfering with mitochondrial respiration, suggesting its potential as an adjuvant therapy to BRAF inhibitors for patients with melanoma brain metastases.

This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.

This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.