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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

New compounds may help treat prostate cancer by reducing cell growth.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Finasteride treats hair loss and prostate issues by lowering certain hormone levels.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.