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Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Testosterone helps human pancreatic cells increase insulin release.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Teak leaf extract contains compounds that could help treat hair loss.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

The inhibitor DPP can promote hair growth.

The herbal hair cream could help treat male pattern baldness by blocking a baldness-related enzyme and might be worth further investigation.

Men with thinner hair from genetic hair loss may be more likely to have an enlarged prostate.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.