7 citations
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January 2017 in “Clinical and medical investigations” This paper reviews the historical use and contemporary relevance of plant-derived cosmetics, focusing on Suriname's herbal cosmetics industry and the potential to establish a beauty products industry there, without presenting new findings.
4 citations
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January 2020 4 citations
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February 2015 in “PubMed” This study found that a minoxidil foamable emu oil emulsion significantly promoted hair growth in animals compared to a marketed 5% minoxidil solution, showing increased hair follicles in the anagenic phase.
4 citations
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August 2023 in “Materials” This review highlights that synthetic biodegradable polymers like PVA, PCL, PLA, PLGA, PU, and PEO/PEG can address the limitations of natural polymers in wound healing, offering improved mechanical properties and slower degradation, thereby enhancing their application as wound dressings.
2 citations
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November 2025 in “International Journal of Molecular Sciences” This review reports that chitosan, a versatile polysaccharide, shows potential for various therapeutic applications due to its chemical modifications, notably in treating non-communicable diseases and wound healing, though further clinical study is needed to confirm these benefits.
1 citations
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March 2021 in “F1000Research” This review discusses plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, as potential alternatives to 5-alpha-reductase inhibitors for prostate cancer treatment, highlighting their promising anti-cancer properties and potentially fewer side effects compared to conventional drugs.
This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.
July 2021 in “Faculty of 1000 Research Ltd” This review discusses the potential of phytochemicals from plants as alternative treatments for prostate cancer, highlighting their possible benefits over current 5-alpha-Reductase inhibitors, but reports no new findings.
June 2021 in “F1000Research” This review explores plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, for their potential use as alternative treatments for prostate cancer, emphasizing their effects on 5-alpha-Reductase enzyme isozymes. It reports no new clinical results.
4 citations
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August 2017 in “Journal of Cosmetic Dermatology” The study found that males with androgenetic alopecia had a significantly lower left-hand 2D:4D digit ratio compared to healthy controls, suggesting this ratio may help estimate future AGA risk.
3 citations
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June 2016 in “Dermatology Reports” This study concluded that the digit-length ratio (2D:4D) does not predict androgenic alopecia development, suggesting prenatal androgen exposure does not predispose men to this condition.
November 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that among vitiligo patients in south-southern Nigeria, there were significant correlations between digit lengths and digit ratio, but further research is needed due to the small sample size.
December 2022 in “The Aging Male” This study found that in male patients, a lower right-handed 2D:4D digit ratio combined with older age correlated with increased severity risk of androgenetic alopecia.
5 citations
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May 2019 in “Anais Brasileiros de Dermatologia” This article discusses the connection between prenatal androgen exposure, marked by the second-to-fourth digit ratio, and seborrheic dermatitis, but reports no new experimental findings.
December 2025 in “Anatomy (International Journal of Experimental and Clinical Anatomy)” In this study, researchers found that the congenital absence of the palmaris longus muscle was relatively uncommon and showed no significant differences according to sex, side, or digit ratio (2D:4D) among individuals assessed using MRI and radiographs.
October 2023 in “Dermatology practical & conceptual” In this review, the authors evaluated the potential of using the second to fourth digit ratio (2D:4D) as a predictor for androgenetic alopecia, suggesting future research directions but not reporting definitive results.
March 2018 in “Benha Journal of Applied Sciences” This study found that while prolactin and DHEA-S levels were higher in women with hirsutism compared to controls, there was no significant correlation between second to fourth digit ratio and hormonal profiles.
3 citations
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February 2019 in “Disease Markers” This study reports that a lower 2D:4D finger length ratio is significantly associated with higher disease activity and reduced spinal mobility in females with ankylosing spondylitis, but not in males.
This case report highlights the successful use of platelet-rich plasma infiltration to treat vasopressin-induced bilateral foot digit gangrene in a 20-year-old female, suggesting its potential in stimulating angiogenesis and wound healing, though further research is necessary to assess its general efficacy.
June 2018 in “Biomedical Journal of Scientific and Technical Research” In this study, a significant negative correlation was observed between the 2D:4D digit ratio and maxillary sinus volume in men, suggesting an androgenic hormone influence on sinus volume development.
This research suggests that the digit ratio, 2D:4D, is unlikely to be a significant indicator of male androgenetic alopecia, contradicting a prominent isolated finding from a previous study.
8 citations
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September 2016 in “Journal of Investigative Dermatology” In this study, Flii overexpression in mice enhanced fingertip regeneration and nail formation after both distal and proximal amputations, suggesting a role in digit and hair follicle regeneration possibly involving Wnt signaling.
3 citations
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September 2021 in “Journal of Clinical Medicine” In this study, fingertip regeneration in mice was associated with specific signaling pathways involving hair follicles and hedgehog signaling, with potential implications for improving human hand injury treatments.
17 citations
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January 1997 in “Cell and Tissue Research” This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.
This study found that activating BMP signaling in rodent and primate models significantly promotes nail and digit regeneration after amputation by enhancing the role of specific nail stem cells, though extreme proximal amputation only permitted partial regeneration without bone reconstruction.
44 citations
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February 2023 in “Cell” In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.
22 citations
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May 1986 in “Clinics in endocrinology and metabolism” This study found that women with lower 2D:4D ratios and fewer middle-phalangeal hairs reported more adverse side effects from oral contraceptives, suggesting these features may predict hormonal contraceptive side effects.
2 citations
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June 2013 in “Journal of Dermatological Case Reports” This article presents a case of Olmsted syndrome in a 5-year-old boy, adding to the limited number of reported cases of this rare keratinization disorder.
December 2024 in “Reports of Vinnytsia National Medical University” In this study, young Ukrainian men with alopecia areata were found to have a "subpathological" body type, characterized by shorter lower limbs and longer upper limbs and torso compared to healthy peers.
March 2020 in “UTUPub (University of Turku)” This study found that self-reported androgen-driven phenotypes, like balding and finger length ratios, were not associated with cancer aggressiveness or biochemical recurrence in prostate cancer after prostatectomy.