June 2026 in “Psychoneuroendocrinology” In this study involving patients with Multiple Sclerosis, higher hair cortisol levels and being Black were linked to poorer cognitive performance, while increased perceived stress and depression were associated with greater fatigue, highlighting distinct associations between objective and subjective stress measures and MS-related outcomes.
This study found that women with PCOS had significant hormonal imbalances, increased central obesity, and a lower 2D:4D digit ratio, suggesting prenatal androgen exposure may play a role in the condition's development.
January 2020 in “AYBU AVESIS” This study found no significant difference in 2D:4D ratios and autism questionnaire scores between acne vulgaris patients and healthy controls, despite investigating potential links in this novel context.
22 citations
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July 2006 in “Annals of The Royal College of Surgeons of England” This case report aims to raise physician awareness about 'toe-tourniquet' syndrome, which can lead to digit loss if not promptly treated, and to prevent its misdiagnosis as child abuse.
10 citations
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October 2016 in “Experimental Dermatology” This essay discusses the role of the nail in mammalian digit tip regeneration and explores whether nail stem cells are solely responsible for this regenerative ability, with no new results presented.
8 citations
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April 2016 in “Anais Brasileiros De Dermatologia” This study found that males with androgenetic alopecia had a significantly lower 2D:4D digit length ratio in the right hand compared to healthy controls, which may indicate prenatal androgen exposure.
September 2023 in “UCrea (University of Cantabria)” In this study, researchers found that mouse digits without nails could not regenerate after amputation, highlighting the necessity of nails for fingertip regeneration and suggesting a potential role for the Lmx1b gene in this process.
1 citations
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May 2018 in “Emergency Nurse” In this article, two case studies of hair tourniquets around digits are discussed, highlighting the condition's potential causes and management strategies, and emphasizing the role of midwives and health visitors in educating expectant mothers to minimize the risk to children.
6 citations
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September 2021 in “Experimental Brain Research” In this study, researchers found that the glabrous skin of the rat forelimb contains sparse Meissner corpuscles and Merkel complexes, with more slowly adapting afferents in the palm and rapidly adapting afferents in the digit extremity.
January 2026 in “Journal of Clinical and Investigative Dermatology” This case report describes a father with HOXC13-associated pure hair-nail ectodermal dysplasia, presenting with severe nail dystrophy affecting all digits and notable hypotrichosis or complete alopecia.
40 citations
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January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
28 citations
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January 2012 in “Case Reports in Medicine” This article discusses Hair-thread Tourniquet Syndrome in children, emphasizing the need for prompt examination and intervention to prevent severe complications, but reports no new clinical results.
7 citations
,
August 2016 in “Nursing for Women's Health” This article reviews the issue of hair-thread tourniquets in infants, emphasizing the importance of awareness for timely diagnosis and suggesting prevention strategies, but reports no new clinical results.
1 citations
,
December 2022 in “BMC Public Health” In this study, among over one million COVID-19 patients, several long-term effects were identified, with age and gender commonly associated, while other social determinants showed limited significant associations.
December 2025 in “Philippine Journal of Internal Medicine” This case report describes a 45-year-old woman with an SLE-SSc overlap syndrome who experienced significant improvement in symptoms after tailored immunosuppressive therapy including prednisone and mycophenolate mofetil.
November 2021 in “Research Square (Research Square)” This study found that numerous long-term effects of SARS-CoV-2 were significantly associated with age and gender, while race, income, and education had limited significance.
48 citations
,
January 2008 in “European Neurology” This study demonstrated that acute thallium poisoning primarily manifests with gastrointestinal issues, polyneuropathy, and dermatological changes, and treatments like hemoperfusion and hemodialysis may improve symptoms.
1 citations
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March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used confocal Brillouin microscopy to observe that a decrease in tissue compressibility occurs during the development and regeneration of axolotl limbs, suggesting mechanical changes linked to regeneration stages undetectable by fluorescence microscopy.
December 1972 in “Archives of Dermatology” This report describes a case of scarring alopecia in a 7-year-old girl, highlighting the presence of inflammation without true sclerosis despite normal bone age and negative fungal tests.
201 citations
,
April 2017 in “Regeneration” This review examines the roles of macrophages and fibroblastic cells in organ injury and repair, discussing their impact on outcomes ranging from regeneration to fibrosis, without presenting new clinical results.
85 citations
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December 2017 in “Developmental Biology” This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
81 citations
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July 2012 in “Translational Psychiatry” In this pilot study, no significant differences were observed between memantine and placebo groups in young adults with Down syndrome on the primary memory outcomes, but some improvement was noted in a secondary measure.
17 citations
,
January 2015 in “International Journal of Trichology” This case report suggests that frontal fibrosing alopecia with nail involvement may be associated with lichen planus and improved with oral dutasteride due to an inflammatory reaction related to androgenetic alopecia.
September 2021 in “Research Square (Research Square)” This study reports that despite rescuing neurulation and skin barrier defects, Grhl3 gene overexpression in mice leads to hearing impairment, hair loss, and other developmental abnormalities, highlighting low tolerance for Grhl3 dysregulation.
January 2018 in “Journal of The American Academy of Dermatology” This study reports various methods used by hair transplant surgeons to count and manage follicular grafts during follicular unit extraction hair restoration, including manual counting and the use of automated or digitalized graft counters.
April 2016 in “Journal of The American Academy of Dermatology” Finasteride effectively treated hidradenitis suppurativa.
21 citations
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April 2004 in “Australasian Journal of Dermatology” This report describes a rare case of hair and nail ectodermal dysplasia in a 3-year-old girl, where treatment with topical minoxidil resulted in minimal improvement after 12 months.
18 citations
,
March 2004 in “Clinics in Dermatology” This review discusses recent advances in understanding the cellular, molecular, and genetic factors contributing to lupus erythematosus and reports no new experimental findings.
2 citations
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April 2016 in “Journal of The American Academy of Dermatology” This study found that dutasteride was more effective than finasteride in increasing total and thick hair count and reducing thin hair count in men with AGA, with both drugs having similar side effect profiles.
1 citations
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January 2024 in “BMJ Case Reports” In this case report, a woman in her 50s was diagnosed with meningitis linked to mixed connective tissue disease after presenting symptoms similar to infectious meningitis, but with no infection detected and serological evidence pointing to the autoimmune condition.