Patient Reported Androgen Driven Phenotypes Do Not Associate With Biochemical Recurrence After Radical Prostatectomy

March 2020 in “ UTUPub (University of Turku) ”

Konsta Kuusento

androgenic alopecia androgen-driven phenotypes digit length acne androgens

TLDR Androgen-driven traits don't predict prostate cancer recurrence.

This study investigated whether self-reported androgen-driven phenotypical features, such as male pattern baldness, acne, and digit length, were associated with the aggressiveness and biochemical recurrence of prostate cancer in a cohort of 628 men who underwent radical prostatectomy. The results indicated that androgenic alopecia, low 2D:4D digit ratio, and acne did not significantly affect the occurrence of biochemical recurrence. Consequently, the study concluded that these phenotypical features were not associated with cancer aggressiveness or recurrence, suggesting that further prospective trials on these features may not be necessary.

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community My Theory Of Androgenic Alopecia

in Research/Science 17 upvotes 2 weeks ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 2 years ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community Sugar and Hair loss connections

in Research/Science 41 upvotes 6 months ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

in Chat 140 upvotes 2 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Hair loss research is a money grab

in Chat 217 upvotes 1 month ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

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