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Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Women with excessive hair growth tend to have shorter index and ring fingers compared to others.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Gonadal hormones may influence sex differences in play fighting in animals, but their effect on human spatial behavior is unclear and needs more research.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.