January 2024 in “Medicinska istrazivanja” This case report describes erosive pustular dermatosis of the scalp in a 55-year-old woman, which improved rapidly with oral antibiotics and topical corticosteroids but resulted in permanent scarring alopecia, emphasizing the need for prompt diagnosis and treatment to minimize scarring.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In a guinea pig model of dermatophytosis, this study found that subcutaneous CD101, dosed once weekly, demonstrated significant clinical and mycological efficacy compared to the vehicle control and the oral antifungal terbinafine, suggesting potential for CD101 in treating fungal skin infections.
This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.
10 citations
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July 2015 in “Journal of Cosmetic Dermatology” This study found elevated tissue levels of DKK-1 in patients with both androgenetic alopecia and alopecia areata compared to controls, suggesting DKK-1 as a potential therapeutic target for these conditions.
February 1996 in “Clinical Pharmacology & Therapeutics” MK-386 reduces sebum DHT levels.
June 2019 in “International journal of dermatology and venereology” This case report highlights a 73-year-old man developing rosacea-like dermatitis after taking icotinib hydrochloride for NSCLC, suggesting awareness of this side effect is important for clinicians.
December 2025 in “Cureus” This case report highlights that scarring alopecia with features of dystrophic epidermolysis bullosa and lichen planopilaris can occur in patients with a COL7A1 mutation, emphasizing the need to recognize concurrent inflammatory causes.
3 citations
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January 2020 in “Journal of Cutaneous and Aesthetic Surgery” This review highlighted that despite existing treatments, chronic nonhealing leg ulcers remain a significant therapeutic challenge, necessitating the development of new methods that are effective, safe, and affordable for patients.
21 citations
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January 2012 in “Annals of Dermatology” This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
2 citations
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September 2024 in “Journal of the American Academy of Dermatology” Deuruxolitinib significantly helps regrow scalp hair in adults with moderate to severe alopecia areata.
August 2025 in “ChemPhotoChem” This study demonstrated that CD anisotropy effectively distinguishes between two polymorphs of finasteride with nearly identical electronic circular dichroism spectra, using imaging and simulated spectra to uncover unique signatures that traditional methods miss.
195 citations
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November 2001 in “The Journal of Cell Biology” This study found that desmocollin 1 is crucial for strong adhesion and barrier maintenance in the mouse epidermis, with its absence leading to skin and hair issues resembling chronic dermatitis.
86 citations
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August 2011 in “Toxicological sciences” In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.
1 citations
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January 2020 in “Progressive Agriculture” This study found that three weekly injections of long-acting tetracycline effectively treated generalized bovine dermatophilosis in a buffalo dairy farm.
3 citations
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August 2021 in “Research Square (Research Square)” This study found that increased mRNA expression of the Ectodysplasin-A2-Receptor, observed across multiple species and tissues, may exacerbate inflammation during aging, suggesting potential benefits of blocking EDA2R/EDA-A2 signaling.
January 2021 in “Online Publication Service of Würzburg University (Würzburg University)” This study examines the use of diphenylcyclopropenone in treating alopecia areata patients at the University Hospital Würzburg and investigates how the treatment affects patients' quality of life.
4 citations
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May 2019 in “Asian Journal of Pharmaceutical Sciences” This study found that a dutasteride tablet formulation using cyclodextrin complex, solubilizing polymer, and surfactant achieved similar bioavailability in beagle dogs to that of a commercial capsule.
4 citations
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August 2016 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report observed that after 6 months of treatment with topical cetirizine and oral vitamin D, hair density and quality improved in three girls with congenital hypotrichosis due to ectodermal dysplasia.
July 2024 in “Journal of Investigative Dermatology” ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.
2 citations
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January 2023 in “Journal of Dermatology” This study reports that various types of alopecia, including permanent alopecia, can persist after an acute DRESS episode, but telogen effluvium and alopecia areata showed clinical improvement with treatment within six months.
7 citations
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August 2010 in “Medicinal Chemistry Research” This study found that some synthesized 17-oximino-5-androsten-3β-yl esters demonstrated stronger cytotoxicity and antiandrogenic activity against prostate cancer cells than finasteride.
2 citations
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January 2023 in “Redox Report” This study found that estradiol significantly reduces cisplatin-induced cochlear hair cell death in mice, likely by activating Nrf2 and phase II detoxification enzymes.
3 citations
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July 2023 in “International Journal of Trichology” This study found that treatment with diphenylcyclopropenone led to more than 75% hair regrowth in 33.3% of patients with alopecia totalis or alopecia universalis, despite notable side effects.
49 citations
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January 2005 in “Dermatology” This case study found that isotretinoin treatment achieved complete resolution of erosive pustular dermatosis of the scalp in a patient, suggesting systemic retinoids as a potential treatment option.
December 2023 in “Reactions weekly” December 2023 in “Reactions weekly” September 2013 in “Reactions weekly” 4 citations
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January 1989
12 citations
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June 2022 in “FARMACIA” This study found that a topical transethosomal system may enhance the skin penetration and deposition of naftifine compared to a marketed cream, potentially overcoming the stratum corneum barrier.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.