Scarring Alopecia in Localized Dystrophic Epidermolysis Bullosa: A Case Report and a Scoping Review

    December 2025 in “ Cureus ”
    Pratiksha Patra, Sairekha Ravichandran, Nishit Patel … Wei-Shen Chen
    Studysummary This case report highlights that scarring alopecia with features of dystrophic epidermolysis bullosa and lichen planopilaris can occur in patients with a COL7A1 mutation, emphasizing the need to recognize concurrent inflammatory causes.
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    Research cited in this study 4

    1. Pathogenesis and Clinical Features of Alopecia in Epidermolysis Bullosa: A Systematic Review Pediatric Dermatology · 2019
    2. Pigmented Hair-Thickening Fibers: A Camouflage Technique for Alopecia in Patients with Epidermolysis Bullosa Skin appendage disorders · 2015
    3. A Histologic Review of 27 Patients with Lichen Planopilaris Journal of the American Academy of Dermatology · 2008
    4. Three Novel Homozygous Point Mutations and a New Polymorphism in the COL17A1 Gene: Relation to Biological and Clinical Phenotypes of Junctional Epidermolysis Bullosa The American Journal of Human Genetics · 1997