Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

HEM-13HDC, a mix of 8 herbal extracts, helps hair grow and affects hair growth at a molecular level.

This study suggests that abnormal hair cycles in Hr mutant mice may be caused by HR protein overexpression, which down-regulates miR-31 and increases Tgf-β2 expression.

This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.

This article discusses the preparation of tritium-labeled testosterone metabolites and reports no new experimental findings.

In this study, oral dienogest combined with ethinylestradiol provided effective contraception with a Pearl Index of approximately 0.2 and improved androgenic symptoms without significant metabolic effects.

This study found that HET extract increased dorsal hair density and VEGF protein expression in a hair growth animal model suggesting its potential efficacy for alopecia treatment.

This study found that the loss of a functional hr gene in mice leads to premature and abnormal hair follicle regression, disrupting normal hair cycling and architecture.

This case report highlights a family member with a confirmed diagnosis of hypotrichosis with juvenile macular dystrophy due to a CDH3 gene mutation, emphasizing the importance of genetic testing for accurate counseling.

This study found that red light at an irradiance of 8 mW/cm² was most effective in promoting growth and modulating signaling pathways in dermal papilla cells treated with dihydrotestosterone, suggesting the need for personalized photobiomodulation treatment approaches for androgenetic alopecia.

This study found that DHEA significantly inhibited growth and induced autophagy in a mouse melanoma cell line, but showed only muffled inhibition and induced apoptosis in a human melanoma cell line.

This study found that deleting all three Tet genes in mice led to shorter hair shafts and altered hair types, with associated changes in gene expression and DNA hydroxymethylation.

This study demonstrated that both HR isoforms are expressed in keratinocytes, but HRDelta1072-1126 lacks corepressor activity and may act as a coactivator by inhibiting HDAC recruitment to the VDR transcriptional complex.

In this study, cyproterone acetate at 2 mg daily was found to be as effective as higher doses in reducing hair growth for hirsute women over 12 months.

This abstract reviews the role of finasteride and potential dual 5alpha-reductase inhibitors in treating benign prostatic hyperplasia, suggesting that dual inhibitors may offer greater DHT suppression and therapeutic advantages, while emphasizing the need for clinical evaluation.

IL-6 contributes to hair loss by shortening the growth phase and causing hair follicles to regress.

This study assessed lipid parameters and serum DHT levels in type 2 diabetes patients, but the abstract does not specify the findings about their association.

In this study, researchers highlight the role of androgens like dihydrotestosterone in the pathophysiology of acne, pointing to the enzyme 5a-reductase type 1 as potentially more active in individuals with acne, which may contribute to hormonal influences in the condition's development.

This study found that transplanting trichogenous dermal cells significantly enhanced the restoration of in vivo-damaged hair follicles in a nude rat model, with a combination of dermal papilla and sheath cells proving more effective than either cell type alone.

In this study, a herbal preparation inhibited the conversion of testosterone to DHT and its binding on hair roots in vitro, suggesting potential as an alternative treatment for androgenic alopecia without the safety concerns associated with finasteride.

This study identified a thiazolidine dione derivative as a potential inhibitor of 15-PGDH that may enhance prostaglandin activity in hair follicles, suggesting its use to support hair regrowth treatments.

A 6-year-old boy developed excessive hair growth after taking diazoxide for low blood sugar.

This study suggests that the mechanical robustness of hair may be enhanced by the binding interactions of keratin-associated proteins, particularly KAP8.1, with intermediate filament proteins.

This report suggests that for prostate cancer patients with cardiovascular disease, prescribing the GnRH antagonist degarelix may reduce cardiac events compared to using GnRH agonists, although prescribing should consider potential cardiac risks, particularly in patients with pre-existing conditions or older age.

This study discusses the impact of alopecia on individuals' appearance and psychological well-being, highlighting how factors like genetics and lifestyle influence hair loss, and explores traditional Ayurvedic approaches for managing and promoting hair regrowth.

This study identified a novel I268T mutation in the vitamin D receptor that reduces its function, contributing to hereditary vitamin D-resistant rickets, and found that a potent vitamin D analog could improve receptor function.

Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.

This study found that the mammalian hairless gene encodes a corepressor protein that interacts with thyroid hormone receptors, providing insights into hair loss syndromes in humans and mice.

This study concluded that the hairless protein interacts with the vitamin D receptor to repress transcription crucial for hair cycling, employing multiple protein interfaces and modulating chromatin structure.

This study found that the protein hairless acts as both a corepressor and coactivator of the vitamin D receptor, influencing gene transcription in a ligand-selective manner.