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This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.

This study found that the vitamin D receptor, but not its ligand, regulates genes involved in hair cycle progression, suggesting a role in integrating hormone signaling pathways for hair and epidermal functions.

This study found that dutasteride affected spinal bone formation in curdlan-treated SKG mice, while DHT treatment reduced osteoblast differentiation in vitro, suggesting that DHT inhibition might unexpectedly increase spinal ankylosis progression in ankylosing spondylitis patients.

This study found that serum 3 alpha-diol G levels in women with idiopathic hirsutism correlated well with their clinical response to treatment, suggesting its usefulness in evaluating treatment outcomes.

The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.

Photobiomodulation helps protect hair follicle cells from damage caused by DHT.

This study describes a genetic mutation in the desmoglein 4 gene linked to localized autosomal recessive hypotrichosis in Pakistani families, showing similarities to animal models with similar hair loss conditions.

This study found that after topical application in rats, 1,24-dihydroxyvitamin D3 absorbed through both the stratum corneum and hair follicles, with about 30% excreted via the faeces.

This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.

This study found that 5-bromo-3,4-dihydroxybenzaldehyde (BDB) promoted hair growth in rat vibrissa follicles by activating Wnt/β-catenin and autophagy pathways and inhibiting the TGF-β pathway in dermal papilla cells.

This study found that dexamethasone treatment reduced cell viability and growth factor expression in human dermal papilla cells, suggesting it inhibits hair growth.

This study found that Gp₄G increased hair length, papilla cell numbers, and versican deposition in treated animals, potentially through alterations in hair follicle phases and nucleotide concentrations.

This review discusses how dehydroepiandrosterone (DHEA) may exert its biological effects through multiple receptors and reports no new clinical results.

In this study conducted at Bangabandhu Sheikh Mujib Medical University, researchers reported that males with androgenetic alopecia had significantly higher levels of serum LH, prolactin, testosterone, DHEA-S, and free androgen index, and lower levels of serum FSH and SHBG compared to those without hair loss.

This study identified complex regulatory elements and interactions involving the Hr gene and HR protein that are crucial for hair follicle formation and cycling in mammals.

This study found that extract of Hura crepitans inhibited androgen-accelerated NT-4 activity and ameliorated the retardation of hair regrowth in dihydrotestosterone-implanted mice, suggesting a potential role for NT-4 inhibitors in AGA.

This article reviews the genetic and phenotypic characteristics of Trichothiodystrophy and discusses the associated DNA repair defects, but does not report new clinical findings.

DHEA therapy improves pubic hair growth and psychological well-being in young females with central adrenal insufficiency.

This study found that canine dermal papilla cells and fibroblasts metabolize androgens differently than human hair follicle cells, indicating species-specific differences in androgen metabolism.

This study systematically reviewed dermatological conditions affecting transgender and gender-diverse individuals, highlighting that testosterone therapy can induce acne in 25–88% of transgender men and alopecia after over two years, while dermatologic care must consider both medical and social complexities.

In this study, hemp seed-derived exosomes (E40) showed potential for counteracting DHT-induced inhibition of feather follicle development in chicken embryos by modulating critical signaling pathways, suggesting a therapeutic approach for alopecia.

A gene deletion in DSG4 causes sparse hair in some Pakistani families.

Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.

This study found that DGAT1 functions as a key enzyme in murine skin to regulate retinoic acid levels and prevent retinoid toxicity, impacting hair cycle and sensitivity to retinol.

This study found that Gynostemma pentaphyllum leaf hydrodistillate (GPHD) promoted hair growth in mice similarly to minoxidil and upregulated growth factor expression via the AKT/β-catenin signaling pathway, with damulin B identified as an active component contributing to these effects.

This study observed that gamma-ray induced apoptosis in ICR mouse hair follicles could be reduced by pretreatments with diethyldithiocarbamate or green tea, suggesting these agents as potential radioprotectors.

Mutations in the DSG4 gene cause specific hair and scalp issues.

This study found that higher dihydrotestosterone (DHT) levels are associated with reduced crowing complexity in Kokok Balenggek roosters.

This study found that transdermal DHT treatment increased penile length in boys with 5α-reductase type 2 deficiency, but post-pubertal growth was limited and carried potential prostate complications.

This study found that dihydrotestosterone treatment may be more beneficial for height in children with 5-α-reductase type 2 deficiency compared to testosterone enanthate, especially in the prepubertal period.