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This study found that the Dongeui Hot Spring Water complex (Dongui Hot Spring Water CPX), containing sea slug extract and panthenol, demonstrated higher antioxidant activity and cell proliferation, suggesting potential benefits for preventing hair loss and improving scalp health.

This study found that in yak hair follicles, TGF-β2 significantly contributes to the transition from growth to regression phases via inducing apoptosis, whereas HSP70 appears to inhibit follicle regression by protecting epithelial cells from apoptosis.

This study found diverse responses to the androgen dihydrotestosterone in rodent tissues, with most androgen-regulated processes being specific to particular tissues.

This study found that recruiting healthy naturally menopausal women for a DHEA therapy trial was challenged by concerns about hormonal treatments and time constraints, impacting study feasibility.

This study found that angiopoietin-1 significantly reduces apoptosis and promotes proliferation in human follicle dermal papilla cells under DHT-induced stress, suggesting its potential as a therapeutic candidate for androgenetic alopecia.

This study indicates that vitamin D3 administration may protect rat hair follicles from radiation-induced damage, as evidenced by maintained follicle numbers and increased Vitamin D receptor activity in treated skin.

This study found that the absence of the vitamin D receptor disrupts hair follicle structure during the first catagen in mice, linked to increased expression of the hairless gene.

Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.

This study found that human dermal γδT-cells can act as stress sentinels and potentially trigger autoimmune responses toward stressed hair follicles, resembling features of alopecia areata.

This study found that while systemic absorption of DHT from liposomes was negligible, the topical biological effect was weaker compared to DHT dissolved in acetone on the female hamster flank organ model.

This survey found that healthcare professionals view a novel nutritional supplement containing a natural DHT inhibitor as a beneficial adjuvant in the treatment of androgenetic alopecia among Indians.

This study found that sleep deprivation in mice can trigger prostatitis by activating the cGAS-STING pathway due to reduced levels of dihydrotestosterone and melatonin, resulting in a pro-inflammatory environment, while recovery sleep can mitigate these effects.

This study found that while prolactin and DHEA-S levels were higher in women with hirsutism compared to controls, there was no significant correlation between second to fourth digit ratio and hormonal profiles.

Human hair follicles have their own thyroid hormone system.

In this study, a TGF-β mimic molecule from Heligmosomoides polygyrus was observed to enhance wound healing in mice, with improved tissue regeneration and specific immune cell recruitment without increased scarring.

This systematic review reported that gender-affirming hormone therapy may lead to changes in hair growth patterns, with differing effects for transgender men and women, potentially impacting quality of life.

This review discusses hormone replacement therapy for menopausal women, emphasizing DHEA's unique ability to convert into sex steroids only in targeted tissues, and reports no new clinical results.

In this study, women experiencing hair thinning who consumed tailored botanical-based nutraceuticals saw significant increases in linear hair growth rate and other hair health parameters over 90 and 180 days, supporting their effectiveness across different life stages.

This study used gas chromatography-mass spectrometry to simultaneously quantify androstenedione, dihydrotestosterone, dehydroepiandrosterone, testosterone, androsterone, etiocholanolone, progesterone, and pregnenolone in human hair, detecting differences in steroid concentrations between male and female samples.

This study found that KH053, combining Panax ginseng and bee-pollen, significantly reduced prostate weight and DHT levels, inhibiting BPH development in a rat model.

This historical review traces the discovery of 5-alpha reductase inhibitors, widely used in urology, from the study of guevedoces, Dominican children with a rare disorder leading to significant androgenization at puberty.

This study found that tetracycline can adhere to hair follicle structures and disrupt cell metabolism, potentially damaging healthy human cells as well as pathogens.

This study found that a hypomorphic mutation in the Hr gene contributes to the development of diet-induced pruritic atopic skin in mice, particularly when combined with dietary deficiencies of polyunsaturated fatty acids and starch.

This study observed that the molecular structure of keratins in hair fibres' discrete transition zone differs in breast cancer patients, with altered lipid ester absorption bands reverting post-cancer removal.

This study found that cyproterone acetate significantly reduced both serum 3α-AdiolG levels and hirsutism scores in women with idiopathic hirsutism, PCOS, or 21-hydroxylase deficiency, suggesting its effectiveness in treating excessive hair growth.

This study found no evidence that HDGF expression transforms melanocytes into tumors in a mouse model, although it may play a role in cell differentiation and tumor progression.

This study found that HPD is a potent activator of hair follicle regeneration, surpassing the efficacy of conventional minoxidil treatment by modulating Wnt/β-catenin signaling and enhancing follicular proliferation, indicating its potential as a non-invasive hair restoration therapy.

This study found that a single intradermal injection of human dermal papilla cells increased hair follicle number and thickness in pigs, suggesting potential effectiveness for hair growth in humans.

This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.