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The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

The document concludes that using a person's own fat cells (SVF) can significantly increase hair thickness and density, suggesting it could be a promising treatment for hair loss.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Ultrasound boosts finasteride's hair growth effects in mice.

Proper hair care and suitable products are essential for men's scalp health and well-being.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

Costunolide helps human hair cells grow and can stimulate hair growth in mice.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.