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This review discusses potential strategies for rejuvenating miniaturizing hair follicles in androgenic alopecia but reports no new clinical results; it explores the idea of using DHT-resistant follicle preservation for long-term hair maintenance.

Hormones cause hair loss by affecting cell growth and weakening cell attraction.

This study found that combining fructose and DHT in rats successfully mimicked the clinical phenotypes of non-lean PCOS, providing a novel rodent model for this condition.

This study found that gonadal steroid hormones influence alopecia areata in C3H/HeJ mice, with estradiol promoting progression and dihydrotestosterone conferring resistance to disease onset.

In this study, creatine supplementation over 12 weeks showed no effect on androgen levels or hair follicle health in healthy young males, challenging the belief that creatine causes hair loss.

This case report describes a 28-year-old woman with facial, abdominal, and thigh hirsutism who showed little improvement after 5 months of Metformin and spironolactone treatment.

This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.

This review discusses the influence of androgens on hair and sebaceous growth, emphasizing that response may depend more on peripheral sensitivity than on hormone levels; it reports no new empirical results.

This study developed a method to measure local steroid hormone concentrations in hair, providing new insights into hormone dynamics associated with androgenetic alopecia.

This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.

This review discusses recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia in males, females, and children, but reports no new clinical results.

This study found that Kyoh®, a flavonol-rich extract from rocket leaves, may promote hair growth by enhancing the expression of hair growth-related genes in laboratory conditions.

In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.

In this study of healthy men, low levels of testosterone and dihydrotestosterone were associated with higher body mass index, fat content, and insulin resistance, but their effects on lipid and glucose metabolism were similar in quality.

In this study, Cyanidin 3-O-arabinoside was found to protect against DHT-induced dermal papilla cell senescence and mitochondrial dysfunction in androgenetic alopecia, restoring hair growth in mouse models.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.

This review discusses the biological and cosmetic aspects of hair aging and reports no new clinical results; it highlights current treatments and future research directions to address both aging factors.

This study found that restoring the skin microbiome significantly improved hair growth and skin condition in androgenic alopecia model mice by modulating the immune-inflammatory balance, highlighting the potential of bacterial-based therapies for hair loss.

This report covers an internship at a pharmacy and hospital where multiple pharmaceutical activities were examined, including the preparation of individualized medication and the comparison of drugs for hypercholesterolemia treatment.

This review highlights the critical role of mitochondrial dysfunction in hair loss, particularly androgenetic alopecia, and explores potential therapies targeting mitochondrial pathways to improve hair health, underscoring the need for further research in this area.

This study using human and animal models found that adipose-derived stem cell exosomes promoted hair growth and counteracted dihydrotestosterone's inhibitory effects, suggesting potential therapeutic applications for androgenetic alopecia.

This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.

Genes and hormones cause hair loss, with four genes contributing equally.

This study suggests that apigenin may stimulate hair growth by downregulating TGF-ß1 gene expression in human epidermal keratinocytes and promoting hair follicle elongation in a rat hair follicle culture.

This article reviews the causal mechanisms of hair follicle disorders, focusing on inflammation, genetics, environment, and hormones, but it reports no new clinical results.

In this study, DHT was observed to have varying effects on hair follicle growth and related protein expression depending on concentration, with the Wnt/β-catenin pathway potentially playing a significant role.

This study found that linoleic acid from Malva verticillata seed extracts may promote hair follicle cell growth and counteract hair loss signaling in a lab setting.

This review examines misconceptions and gaps in the understanding of androgenic alopecia (AGA) etiopathogenesis, offering new perspectives but no new experimental results.

This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.