research A Hair Growth Questionnaire for Use in the Evaluation of Therapeutic Effects in Men
The questionnaire effectively measures men's perceived hair growth and can distinguish between different treatments and dosages.
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research Topical Treatment with the Bacterium-Derived c-Met Agonist InlB321/15 Accelerates Healing in the Abrasion Wound Mouse Model
Applying InlB321/15 to wounds sped up healing in mice.
research The Editor's Choice: Summary of Studies on Skin and Hair Conditions
UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.
research Comparison of Comedolytic Effect of Benzoyl Peroxide and Adapalene in Rhino Mice
Benzoyl peroxide and adapalene gels work differently to reduce acne in mice.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Liposomal Systems as Drug Delivery Vehicles for Dermal and Transdermal Applications
Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
research Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research Hair Cycle-Specific Expression of Versican in Human Hair Follicles
Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
research Mechanical Forces in Skin Disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Multi-Layered Environmental Regulation on the Homeostasis of Stem Cells: The Saga of Hair Growth and Alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a
Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.
research Microarray Analysis of Androgenetic and Senescent Alopecia: Comparison of Gene Expression Shows Two Distinct Profiles
The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
research Erythropoietin Promotes Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice
Erythropoietin helps hair grow and could be a potential treatment for hair loss.
research A Preliminary Study of Differentially Expressed Genes in Expanded Skin and Normal Skin: Implications for Adult Skin Regeneration
The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality
Minoxidil and finasteride work best for hair loss; more research needed.
research Finasteride and Androgenic Alopecia: From Therapeutic Options to Medical Implications
Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
research Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner
PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
research Randomized Controlled Trial on a PRP-Like Cosmetic with Biomimetic Peptides for the Treatment of Alopecia Areata
The PRP-like cosmetic with biomimetic peptides is potentially effective and safe for treating alopecia areata.
research In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia
Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.
research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ
Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Finasteride for Hair Loss: A Review
Finasteride helps hair growth but may cause sexual side effects and depression.
research Exogenous Stimulations Change Nude Mouse Hair Cycle Pattern
External treatments can change hair growth patterns in nude mice.
research Sequence and Expression of Human Hair Keratin Genes
Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
research Scalp Hair Regrowth Is Associated With Improvements in Health-Related Quality of Life and Psychological Symptoms in Patients With Severe Alopecia Areata: Results From Two Randomized Controlled Trials
Regrowing scalp hair improves quality of life and reduces anxiety and depression in severe alopecia areata patients.
research Runx1 Transcription Factor Is Involved in the Regulation of KAP5 Gene Expression in Human Hair Follicles
Runx1 helps control the KAP5 gene in human hair follicles.
research Efficacy and Safety of Combinational Therapy Using Topical Minoxidil and Microneedling for the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Using minoxidil with microneedling increases hair count for hair loss without serious side effects.