This study developed and tested continuous implanters for dermal papilla cell aggregates, finding that the bar-cartridge type implanter is the most effective design for continuous cell implantation in androgenetic alopecia research.
April 2025 in “Journal of Cosmetic and Laser Therapy” This study found that both microneedle delivery and intradermal injection of platelet-rich plasma were similarly effective for treating androgenetic alopecia, but microneedle delivery caused significantly less pain.
June 2024 in “Annals of the College of Medicine Mosul/Annals of the College of Medecine” This study explored the use of microneedling for dermatological disorders, highlighting its benefits like increased collagen and elastin production, dermal thickening, and skin rejuvenation, making it suitable for conditions such as scars, stretch marks, and photoaged skin.
40 citations
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February 2020 in “Experimental and Therapeutic Medicine” This study found that autologous serum platelet-rich plasma improved skin quality and reduced wrinkles, texture, and pores in healthy females, partly by regulating the expression of MMP-1, tyrosinase, fibrillin, and tropoelastin.
25 citations
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September 2019 in “PubMed” This review discusses the therapeutic potential of platelet-rich plasma in dermatology and highlights the need for standardized treatment protocols, but reports no new clinical results.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the popularity and mechanisms of Platelet Rich Plasma therapy for skin rejuvenation and hair loss, but it reports no new clinical results.
16 citations
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July 2000 in “Dermatologic surgery” This paper contains author contact information and disclosures without reporting new research findings or results.
November 2025 in “Bioengineering” In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
September 2015 in “Veterinary Dermatology” This study found that microneedling induced nearly complete hair regrowth in two Pomeranians with alopecia X, suggesting it may be a promising alternative treatment for similar hair cycle arrest disorders.
July 2025 in “Dermatologic Surgery” August 2016 in “Anaplastology” This study reports that controlled release PRP therapy using dalteparin and protamine micro-particles may be effective for hair growth and skin rejuvenation in women.
4 citations
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April 2016 in “Journal of The American Academy of Dermatology” Microneedling with platelet-rich plasma can improve different types of hair loss.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the use of Platelet Rich Plasma therapy for skin rejuvenation and hair loss and reports no new clinical results, noting its minimally invasive nature and effect on skin texture and elasticity.
1 citations
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January 2026 in “International Journal of Dermatology” In this study, a case of dissecting cellulitis of the scalp was reported in a man after starting dupilumab therapy, highlighting potential immune pathways involved and the importance of recognizing such paradoxical inflammatory reactions to prevent irreversible alopecia.
January 2026 in “JPRAS Open” In this pilot study, PDLLA scalp microinjections showed improvement in physician-rated Global Aesthetic Improvement Scale scores over 12-24 weeks for 90% of patients with non-scarring alopecia, with no serious adverse events reported, although findings remain preliminary due to methodological limitations.
March 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” In this study, researchers compared the efficacy of platelet-rich plasma with microneedling versus microneedling alone for treating androgenic alopecia in 50 patients, though results are not reported in the abstract.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This pilot clinical trial observed that combining subcision using a blunt cannula with platelet-rich plasma injections and microneedling for post-acne rolling scars was associated with a significant positive correlation between physician satisfaction and age of acne onset.
7 citations
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February 2022 in “Frontiers in Medicine” This study found that combining microneedling with PRP was more effective than microneedling alone for improving acne scars, with higher patient satisfaction and no significant increase in severe side effects.
4 citations
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April 2024 in “Cellular and Molecular Biology” In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.
July 2022 in “European Journal of Dermatology” In this study, researchers found that patients with psoriasis had a higher probability of achieving and maintaining a clinical response using brodalumab compared to ustekinumab over 52 weeks, as measured by a multistate modelling approach based on absolute PASI scores.
25 citations
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April 2008 in “Archives of Dermatological Research” This study found that transplanted microencapsulated dermal papilla cells in rat footpads can regenerate hair follicles and sebaceous gland structures, suggesting a potential substitute for fresh dermal papillae cells.
51 citations
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October 2002 in “Archives of dermatology” This case study of a patient with dissecting cellulitis of the scalp found that multiple medications, including isotretinoin, achieved only modest improvement, and symptoms returned after treatments were stopped.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
June 2026 in “The Journal of Cosmetic Medicine” This narrative review reports that scalp micropigmentation offers immediate cosmetic improvements in hair density appearance, but does not promote actual hair regrowth and results vary based on the operator's skill.
January 2024 in “Dermatologic Surgery” This abstract pertains to a dermatology-related academic profile without reporting any specific study findings. Results or research details are not provided.
October 2022 in “Hair Transplantation” This article discusses the temporary scalp trichopigmentation procedure, detailing its unique approach compared to traditional scalp micropigmentation, and reports no new clinical findings.
February 2026 in “Skin Appendage Disorders” This study found that scalp microinfusion with dutasteride using microneedling and tattoo devices appears safe and shows promise as a treatment for male androgenetic alopecia, resulting in stabilization or improvement in 96.7% of patients, although further controlled studies are needed.
16 citations
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April 2000 in “Contact dermatitis” In this report, a 19-year-old Japanese man experienced severe and prolonged urticarial reactions following treatment with diphenylcyclopropenone for alopecia universalis, emphasizing the need for caution with potent sensitizers.
4 citations
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July 2024 in “Cureus” In this report, researchers observed that a single treatment using a combination of hyperdiluted calcium hydroxylapatite, platelet-rich plasma, and hyaluronidase improved neck wrinkles and skin laxity in two patients, indicating preliminary evidence for the safety and efficacy of this novel therapy.
6 citations
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September 2021 in “AESTHETIC OROFACIAL SCIENCE” This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.