Platelet-Rich Plasma for Androgenetic Alopecia: Intradermal Injection or Microneedle Delivery?

    April 2025 in “ Journal of Cosmetic and Laser Therapy ”
    Ping Lu, Mingyi Liao, Xinyu Qiu … Cong You
    Studysummary This study found that both microneedle delivery and intradermal injection of platelet-rich plasma were similarly effective for treating androgenetic alopecia, but microneedle delivery caused significantly less pain.
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    Research cited in this study 26

    1. Targeted Immunotherapy for Hair Regrowth and Regeneration Frontiers in medicine · 2023
    2. Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/Beta-Catenin Pathway Stem Cells International · 2023
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    5. Androgenetic Alopecia: Clinical Features and Trichoscopy DOAJ (DOAJ: Directory of Open Access Journals) · 2022
    6. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways Frontiers in Medicine · 2022
    7. Platelet Rich Plasma Application by Dermapen Microneedling and Intradermal Point-by-Point Injection Methods, and Their Comparison with Clinical Findings and Trichoscan in Patients with Androgenetic Alopecia Dermatologic Therapy · 2021
    8. Effective Strategies to Reduce Pain During Platelet-Rich Plasma Scalp Injections: A Randomized Split-Scalp Study 2021
    9. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    10. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    11. Platelet-Rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-Controlled Pilot Study Acta dermato-venereologica · 2020
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    13. Modified Basic And Specific (BASP) Classification For Pattern Hair Loss International Journal of Dermatology · 2019
    14. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
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    16. Systematic Review of Platelet-Rich Plasma (PRP) Preparation and Composition for the Treatment of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2018
    17. Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia Archives of Dermatological Research · 2018
    18. Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017
    19. Identification of Key Genes Induced by Platelet-Rich Plasma in Human Dermal Papilla Cells Using Bioinformatics Methods Molecular Medicine Reports · 2016
    20. A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia Dermatologic Surgery · 2016
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    22. Changes in the Sebaceous Gland in Patients with Male Pattern Hair Loss (Androgenic Alopecia) Journal of Cosmetic Dermatology · 2015
    23. Trichoscopic Findings of Androgenetic Alopecia and Their Association with Disease Severity Journal of Dermatology · 2015
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    1. Strategies to Minimize Pain During Platelet-Rich Plasma Scalp Injections Journal of The American Academy of Dermatology · 2021