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This study found that dermal papilla cells may play a critical role in hair follicle development and cycling by promoting epidermal proliferation and potentially mediating systemic factors that influence follicle behavior.

This study found that engineered reconstituted skin can form morphogenetic units that promote tissue patterning and hair regeneration, with certain signaling pathways restoring this ability in adult and fetal cells.

This study found that mechanical and chemical interactions in skin organoids are crucial for initiating mesenchymal-epithelial interactions necessary for hair follicle regeneration.

This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.

This study observed that the mechanical connection between hair follicles and connective tissue in human fetal scalp skin is weaker than in the corresponding skin components, reflecting dynamic processes in hair growth.

This study demonstrated that a mechanical-chemical cascade involving dermal cell contraction and the activation of Piezo1 in epidermal cells is crucial for initiating interactions necessary for hair follicle regeneration in skin organoids.

The researchers reported that hair follicle germinative epidermal cells can form complex structures when associating with papilla cells in culture, unlike other types of epidermal cells.

This study found that treating human dermal fibroblast cells with ginsenoside Rd increased the expression of mRNA associated with the dermal-epidermal junction, suggesting potential as an anti-aging cosmetic ingredient.

This review outlines the various fibroblast subsets in the skin dermis, their origins, and their influence on epidermal stem cell behavior, highlighting the role of the local dermal niche in stem cell plasticity.

This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.

This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.

This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.

This study found that mutant mice with the we/we wal/wal genotype exhibit significant defects in hair shaft structure and epidermis stratification, correlating with postnatal alopecia symptoms.

In this study, AMACO was found to be non-essential for the formation or function of anchoring cords in mice, despite its presence in the structure.

This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.

This study found that elevated STAT5 levels are linked to improved hair-inducing capabilities in human dermal papilla cells, and reducing STAT5 impairs hair follicle induction.

This study demonstrates that incorporating human neopapilla into reconstructed human skin can initiate hair follicle morphogenesis by stimulating epidermal invagination and maintaining follicle-inductive properties in vitro.

This review discusses the role of stem cell heterogeneity and compartmentalization within the epidermis and highlights their significance as niches for neighboring cells, without reporting new experimental results.

This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.

This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

This study applied a new RGB trichrome stain to human skin samples, revealing distinct structural staining in normal tissues and potential proteoglycan-rich zones in hair follicles.

This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.

This study found that composite skin constructs containing dermal papilla cells promoted better skin healing and hair regeneration in nude mice, highlighting their role in tissue-engineered skin for severe injuries.

This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.

This study found that 3D microtissue models of dermal papilla cells can enhance the ability to induce hair-follicle neogenesis in vivo, offering potential for controlled cell production in follicle regeneration.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

Different types of stem cells and their environments are key to skin repair and maintenance.

This article reviews advancements in understanding skin regeneration and suggests that bioengineering skin surrogates may soon enhance treatments for skin trauma, but it presents no new clinical findings.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.