The review suggested the study needed to clarify its purpose, compare with non-immortalized cells, and provide more details on methods.
Scientists improved how to grow mouse skin cells in the lab and created a long-lasting cell line, but didn't fully explain its advantages or compare it to normal cells.
April 2016 in “Journal of Investigative Dermatology” Wnt ligands, produced by dermal papilla cells, are essential for adult hair growth and regeneration.
April 2016 in “Journal of Investigative Dermatology” Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
January 2008 in “Journal of Practical Medical Techniques” Microencapsulated cells can regenerate hair follicles in rat ears.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
44 citations,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
21 citations,
October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
16 citations,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
12 citations,
January 2018 in “Biomaterials Science” Softer hydrogel surfaces help maintain hair growth-related functions in skin cells.
1 citations,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cell-derived exosomes can help stem cells grow hair.
March 2023 in “Scientific reports” Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
Testosterone and dihydrotestosterone can slow down the growth of certain hair follicle cells.
3 citations,
May 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
2 citations,
August 2023 in “Ecotoxicology and environmental safety” Vitamin A helps rabbit skin cells grow and survive heat stress.
15 citations,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
92 citations,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
14 citations,
March 2022 in “Journal of Biomedical Science” Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
August 2021 in “Journal of Investigative Dermatology” Stress causes hair loss by making the body produce cortisol, which stops hair cells from growing.
December 2022 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” Natural extracts like ginseng, green tea, shiitake, and aloe vera may help prevent hair loss by protecting hair-related cells.
October 2023 in “Ho Chi Minh City Open University Journal of Science - Engineering and Technology” Human hair follicle cells have specific features.
3 citations,
November 2022 in “Molecules/Molecules online/Molecules annual” The substances improved hair regrowth and protected hair cells in humans and mice.
314 citations,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
57 citations,
November 1998 in “Wound Repair and Regeneration” Hair papilla cells can create and regenerate hair bulbs under the right conditions.
46 citations,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
33 citations,
September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
28 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cells are crucial for hair growth and can induce new hair follicles.
24 citations,
January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
23 citations,
February 2015 in “International Journal of Molecular Sciences” Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.