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This study reports that mutations in human L-PGDS affect the entrance and exit of ligands in its binding cavity, suggesting these residues play a role in ligand interaction processes.

LDL apheresis lowers inflammation and cardiovascular risk by reducing CRP levels long-term.

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.

This study observed that using an environmentally friendly bovine milk permeate effectively and cleanly removes wool from sheepskins without harming the skin, and results in smoother leather compared to traditional chemical methods.

This study developed a sensitive method to precisely determine hair lipid composition, demonstrating specific lipid changes from the root to the tip in untreated hair fibers from two women.

This review examines the design and evaluation parameters of depilatory formulations but reports no new empirical findings.

This study found that dexpanthenol treatment reduced inflammation, oxidative stress, and apoptosis in rats, providing a protective effect against lipopolysaccharide-induced cardiac and endothelial damage.

This review highlights the limited research on sebocyte lipid droplets and their proteins despite their role in sebocyte differentiation and potential involvement in skin diseases like acne and alopecia, and reports no new results.

This review outlines how peptidyl arginine deiminases (PADIs) and protein citrullination are involved in hair follicle regeneration and inflammatory alopecia, but presents no new clinical findings.

This study reviewed various lipolytic agents for reducing submental fat and highlighted that while deoxycholic acid is FDA-approved, other compounds like phosphatidylcholine with deoxycholate lack cosmetic approval due to safety concerns. Understanding these agents' mechanisms and anatomy is crucial for safe fat reduction applications.

This document extends previous recommendations by the National Lipid Association for managing dyslipidemia, focusing on lifestyle therapies, special patient groups, and strategies to enhance adherence and patient outcomes.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.

In this study, researchers identified two novel peptidylarginine deiminases from treated rat keratinocytes, both showing enzyme activity with PAD‐R11 reflecting a characteristic of epidermal enzymes.

This study demonstrated that de novo designed bifunctional proteins can target and degrade BCL-xL, leading to cell apoptosis, suggesting a new approach to targeted protein degradation therapy.

This study found that pure linoleate deficiency in rats caused significant reductions in the accumulation of n-6 polyunsaturates and mild symptoms like growth retardation, compared to classical essential fatty acid deficiency.

This correspondence reports the case of a young woman with severe lipid storage myopathy due to a rare mutation, who showed significant temporary improvement with plasmapheresis and immunoglobulin treatment before stabilizing with riboflavin and coenzyme Q10 supplementation, challenging the initial assumption of an immune-mediated condition.

In this study, researchers purified and cloned rat peptidylarginine deiminase type III, demonstrating its activity and specific expression in the epidermis and hair follicles.

In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.

The study found that a modified two-step enzyme digestion method was an efficient and rapid technique for isolating human axillary dermal papilla cells from a few specimens.

The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.

This study found that paeonol-loaded liposomal gels demonstrated antioxidant effects and relieved inflammation in AD-like mice, suggesting potential benefits for treating atopic dermatitis.

This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.

This study found that incorporating steroid hormones into DPPC liposomes altered their physicochemical properties, including size, zeta potential, and phase transition temperatures.

This study found that both hard and soft selenium disulphide-based detergents significantly increased triglyceride levels in human hair, suggesting enhanced sebum production with reduced lipolytic activity, but showed no significant differences between their effects.

This review discusses recent findings on fibrotic lipodystrophy, highlighting the critical roles of lipid-filled cells in tissue function and their loss during fibrogenesis, with implications for fibrosis in tissues like skin, lung, and liver.

This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.

This study found that liposomes coated with cationic polymers, chitosan and Eudragit EPO, showed improved physicochemical stability and enhanced skin diffusion of aciclovir and minoxidil compared to uncoated liposomes.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.