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Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Finasteride helps treat hair loss by blocking enzyme activity.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Licorice extract helps hair growth and may treat hair loss.

12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Finasteride effectively blocks enzyme causing male pattern baldness.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

The compounds tested could potentially treat hair loss and alopecia.

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.