February 2026 in “Nature Communications” In this study, researchers created a detailed human skin cell atlas by analyzing over 700,000 cells, finding that disrupted communication among specific immune and stromal cell subsets may play a key role in initiating and sustaining chronic skin inflammation in atopic dermatitis.
232 citations
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January 2002 in “Mechanisms of development” This study reports that the differential expression patterns of three retinaldehyde dehydrogenases suggest a regulated need for retinoic acid synthesis in various organs during late mouse organogenesis.
46 citations
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December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, researchers observed that testicular 17β-hydroxysteroid dehydrogenase deficiency in an inbred Arab population in Israel leads to genital ambiguity at birth and progressive virilization after puberty.
June 2018 in “Journal of evolution of medical and dental sciences” In this study, polycystic ovarian disease was identified as a prevalent chronic endocrinopathy among women of reproductive age, with common dermatological symptoms such as hirsutism, acne, and androgenic alopecia.
March 2005 in “Journal of The American Academy of Dermatology” Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.
29 citations
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December 2004 in “Developmental biology” In this study, forced expression of the transcription factor cDermo-1 in chicken dermis led to the formation of ectopic feather buds and enhanced feather growth, demonstrating its role in initiating skin appendage development.
51 citations
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February 2006 in “Clinics in Dermatology” This review discusses the physiological changes in the female body during pregnancy, relating them to hormonal shifts, and comments on treatment considerations, but it presents no new research findings.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” In this study using rats, finasteride-induced DHT deficiency led to morphological changes in seminiferous tubules, linked with altered junctional protein expression, potentially impairing fertility.
245 citations
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April 2009 in “Circulation Research” This study found that human fetal CD133+ progenitor cells and their conditioned medium accelerated wound healing and promoted angiogenesis in a mouse model of ischemic diabetic ulcers through paracrine mechanisms involving Wnt signaling.
May 2026 in “Journal of Pharmacognosy and Phytochemistry” This review discusses the renaming of Polycystic Ovary Syndrome to Polyendocrine Metabolic Ovarian Syndrome, reflecting its broader recognition as a multisystem metabolic-endocrine disorder, and reports no new clinical results.
October 2023 in “Research Square (Research Square)” This study developed a composite product from decellularized human placental connective tissue matrix and placental extract, finding that the combination showed improved biochemical and mechanical properties compared to each component alone, suggesting its potential use for treating chronic and deeper wounds.
3 citations
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September 2024 This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.
41 citations
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October 2017 in “International Journal of Women's Dermatology” This review provides an overview of the physiologic skin changes during pregnancy but reports no new findings, emphasizing the need for physicians to distinguish between benign and potentially pathological conditions.
In this study on Drosophila embryos, researchers observed that the Slit/Robo signaling pathway is crucial for the collective migration and proper positioning of Posterior Signaling Center cells within the hematopoietic niche, highlighting its role in niche assembly and cellular organization.
30 citations
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May 2019 in “Scientific Reports” This study found enhanced remyelination in the corpus callosum of late pregnant rats compared to virgin and postpartum rats, suggesting a pregnancy-associated promyelinating effect mediated, in part, by the GABA A receptor system.
37 citations
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February 2007 in “Experimental Dermatology” This study found that PDCD4 protein expression is reduced in various skin cancers compared to normal skin, suggesting its potential role in preventing or treating certain skin cancers.
October 2020 in “Stem cells” This study highlights a novel connection between the DNMT3B enzyme, metabolic flux, and the self-renewal and differentiation of human embryonic stem cells.
January 2024 in “JMIR Dermatology” Few dermatology programs mention gender-affirming care, highlighting a need for better training and visibility.
53 citations
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September 2013 in “Journal of Investigative Dermatology” This study suggests that cultured hair follicle dermal sheath cup cells exhibit immune privilege properties, partly through the expression of PD-L1, which impacts co-cultured immune cells' behavior.
16 citations
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December 2017 in “Journal of Pediatric and Adolescent Gynecology” In this study, the researchers found that the choice of diagnostic criteria significantly affects the rate of PCOS diagnosis in adolescents.
This review highlights the increasing global incidence and broad socio-economic impact of celiac disease, emphasizing the need for improved recognition and management to address its multidimensional implications, including comorbidities and dietary challenges.
20 citations
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May 1998 in “PEDIATRICS” This correspondence highlights a study on early pubertal development in young girls, noting that early pubic hair and breast development in African-American girls is likely due to increased androgen production, not estrogen or exogenous causes.
254 citations
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January 2012 in “Nature Reviews Molecular Cell Biology” This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.
February 2026 in “Indian Journal of Community Health” Among female doctors in Dakshina Kannada, India, this study found a 21.25% prevalence of PCOS, significantly associated with marital status but not working hours, indicating a need to prioritize PCOS awareness and management among healthcare professionals.
6 citations
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December 2022 in “International Journal of Molecular Sciences” This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.
90 citations
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August 2004 in “Physiological Genomics” This study found that coculturing human hair follicle keratinocyte stem cells with dermal papilla cells increased expression of the hair-specific keratin 6hf gene, which requires β-catenin/lef-1 signaling for hair differentiation.
This study found that inhibiting apoptosis during hair follicle regression in mice disrupted hair regeneration, causing delays and alterations in stem cell niche architecture and associated tissue remodeling processes.
April 2026 in “Dermatology and Therapy” This review discusses the various skin changes, pregnancy-specific dermatoses, and medication management related to dermatologic health during pregnancy, aiming to provide clinicians with an evidence-based guide for diagnosis and treatment.
October 2025 in “Dermatology Practical & Conceptual” In this study, UVFD and sUVRD techniques revealed distinctive characteristics of GD lesions, suggesting that GD might be more common in younger individuals and females than previously thought, possibly due to underdiagnosis. Incorporating dermatoscopy in exams may help improve GD detection and management.