Cutaneous Manifestations of Polycystic Ovarian Disease

June 2018 in “ Journal of evolution of medical and dental sciences ”

Thakur Rajeev Singh, Sathaiah Sudhamalla

hirsutism acne androgenic alopecia acanthosis nigricans seborrhoea impaired glucose tolerance type II diabetes cardiovascular diseases hair loss oily skin insulin resistance heart disease

TLDR Skin problems like excessive hair growth, acne, and dark skin patches can be signs of Polycystic Ovarian Disease, which may also be linked to family history and a risk for diabetes.

In 2018, a study involving 50 patients with Polycystic Ovarian Disease (PCOD) found that dermatological issues such as hirsutism (84%), acne (70%), androgenic alopecia (32%), acanthosis nigricans (56%), and seborrhoea could serve as markers for identifying PCOD. The study also revealed that 67% of women with androgenic alopecia had PCOD, and 42% of the subjects had a family history of PCOD, suggesting a hereditary link. Additionally, 10% of the women had impaired glucose tolerance, a risk factor for type II diabetes and cardiovascular diseases. The researchers concluded that more research was needed to understand the genetic and environmental factors contributing to PCOD.

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research Ovarian SAHA Syndrome Is Associated With a More Insulin-Resistant Profile and Represents an Independent Risk Factor for Glucose Abnormalities in Women With Polycystic Ovary Syndrome: A Prospective Controlled Study

28 citations , December 2013 in “Journal of The American Academy of Dermatology”

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

research Full Investigation of Patients With Polycystic Ovary Syndrome (PCOS) Reveals Significant Differences and Undiagnosed Morbidity

29 citations , November 2011 in “Human Fertility”

Many women with PCOS have undiagnosed health issues and show different symptoms based on the clinic they visit.

research Hirsutism Scoring in Polycystic Ovary Syndrome: Concordance Between Clinicians' and Patients' Self-Scoring

10 citations , December 2010 in “Fertility and Sterility”

Patients with PCOS tend to score their hirsutism higher than clinicians, making self-scoring less useful for diagnosis.

research The Frequency of Polycystic Ovary Syndrome in Females with Resistant Acne Vulgaris

17 citations , June 2010 in “Journal of Cosmetic Dermatology”

Many women with hard-to-treat acne also have PCOS.

research Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

67 citations , February 2010 in “Acta Obstetricia et Gynecologica Scandinavica”

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

research Visually Scoring Hirsutism

288 citations , June 2009 in “Human reproduction update”

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

research What Every Physician Should Know About Polycystic Ovary Syndrome

33 citations , September 2008 in “Dermatologic therapy”

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment

21 citations , December 2007 in “Primary Care”

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

research Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome

97 citations , July 2006 in “Dermatologic therapy”

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

research Definitions, Prevalence, and Symptoms of Polycystic Ovaries and Polycystic Ovary Syndrome

278 citations , October 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”

Polycystic ovaries are defined by having 12 or more small follicles in each ovary and are found in up to 33% of women, while Polycystic Ovary Syndrome (PCOS) is the most common hormone disorder in women of reproductive age, potentially increasing risk of obesity, diabetes, and heart diseases.

research Androgen Excess in Women: Experience with Over 1000 Consecutive Patients

947 citations , February 2004 in “The Journal of Clinical Endocrinology and Metabolism”

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

research Prevalence of Polycystic Ovaries in Women with Androgenic Alopecia

84 citations , November 2003 in “European journal of endocrinology”

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.