Cutaneous Manifestations of Polycystic Ovarian Disease

June 2018 in “ Journal of evolution of medical and dental sciences ”

Thakur Rajeev Singh, Sathaiah Sudhamalla

hirsutism acne androgenic alopecia acanthosis nigricans seborrhoea impaired glucose tolerance type II diabetes cardiovascular diseases hair loss oily skin insulin resistance heart disease

Studysummary In this study, polycystic ovarian disease was identified as a prevalent chronic endocrinopathy among women of reproductive age, with common dermatological symptoms such as hirsutism, acne, and androgenic alopecia. Our plain-language summary of this paper — not a Tressless recommendation.

In 2018, a study involving 50 patients with Polycystic Ovarian Disease (PCOD) found that dermatological issues such as hirsutism (84%), acne (70%), androgenic alopecia (32%), acanthosis nigricans (56%), and seborrhoea could serve as markers for identifying PCOD. The study also revealed that 67% of women with androgenic alopecia had PCOD, and 42% of the subjects had a family history of PCOD, suggesting a hereditary link. Additionally, 10% of the women had impaired glucose tolerance, a risk factor for type II diabetes and cardiovascular diseases. The researchers concluded that more research was needed to understand the genetic and environmental factors contributing to PCOD.

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Research cited in this study

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research Ovarian SAHA Syndrome Is Associated With a More Insulin-Resistant Profile and Represents an Independent Risk Factor for Glucose Abnormalities in Women With Polycystic Ovary Syndrome: A Prospective Controlled Study

28 citations , October 2013 in “Journal of The American Academy of Dermatology”

In this study, ovarian SAHA was found to be independently associated with a more insulin-resistant profile and increased risk of glucose abnormalities in women with PCOS, beyond common risk factors.

research Full Investigation of Patients With Polycystic Ovary Syndrome (PCOS) Reveals Significant Differences and Undiagnosed Morbidity

29 citations , November 2011 in “Human Fertility”

This study reports significant variability in PCOS symptoms across women attending infertility, gynecology, endocrine, and dermatology clinics, highlighting the importance of recognizing diverse presentations and associated health risks like impaired glucose tolerance and diabetes.

research Hirsutism Scoring in Polycystic Ovary Syndrome: Concordance Between Clinicians' and Patients' Self-Scoring

10 citations , June 2010 in “Fertility and Sterility”

In this study, patients with polycystic ovary syndrome self-reported higher hirsutism scores compared to clinician assessments, but only clinician scores correlated with biochemical markers of hyperandrogenism.

research The Frequency of Polycystic Ovary Syndrome in Females with Resistant Acne Vulgaris

17 citations , June 2010 in “Journal of Cosmetic Dermatology”

Many women with hard-to-treat acne also have PCOS.

Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

research Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism

67 citations , February 2010 in “Acta Obstetricia et Gynecologica Scandinavica”

In this study, hirsutism in women with PCOS was strongly associated with hyperandrogenism and metabolic abnormalities, while acne and androgenic alopecia were not effective markers for hyperandrogenism.

research Visually Scoring Hirsutism

288 citations , June 2009 in “Human reproduction update”

This review examines various methods for assessing hair growth in women, highlighting the usefulness of the mFG visual scoring method for diagnosing hirsutism despite its limitations.

research What Every Physician Should Know About Polycystic Ovary Syndrome

33 citations , September 2008 in “Dermatologic therapy”

This review describes the clinical evaluation and management options for women with polycystic ovary syndrome, focusing on its endocrine and metabolic implications, but reports no new results.

research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment

21 citations , December 2007 in “Primary Care”

This article reviews the challenges in treating PCOS, noting the potential benefits of insulin sensitizers on ovulatory function and pregnancy outcomes, and calls for more long-term studies on metabolic interventions.

Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome