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150-180 / 1000+ resultsresearch Ipsilateral post-cast hypertrichosis and dyshidrotic dermatitis
This case report describes an individual who developed both localized hypertrichosis and ipsilateral dyshidrotic dermatitis following multiple fractures and cast application, with symptom resolution similar to when these conditions occur independently.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry
This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.
research Recent advances in X-ray microanalysis in dermatology.
This study found that electron and proton microprobe analysis can reveal differences in element distribution within human hair and epidermis, although no significant water content differences were noted between atopic eczema and normal skin.
research Coordinating the Sculptors: Ectodysplasin-A (EDA) Signaling Cross-Talk with Skeletogenic Pathways
This review examines the complex role of the Ectodysplasin-A pathway in skeletal morphogenesis, emphasizing its interaction with other key signaling pathways, and reports no new experimental findings.
research The 39th Manfred Donike workshop on doping analysis
This collection from the 2021 Manfred Donike Workshop outlines advancements in doping detection, highlighting new test methods and challenges, with a focus on steroidal substances, peptide hormones, and gene doping analysis.
research Supplementary material from "Giant axonal neuropathy alters the structure of keratin intermediate filaments in human hair"
This study found that keratin intermediate filaments in the hair of patients with giant axonal neuropathy were structurally altered, resulting in hair that was stiffer, stronger, and more extensible.
research Chapter 28. Vitamin D: Production, Metabolism, Mechanism of Action, and Clinical Requirements
This chapter discusses the production, metabolism, and mechanism of action of Vitamin D, including its role in calcium and phosphate metabolism and its function in the epidermis and hair follicles, without presenting new research findings.
research Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine
This study found that the medication dyclonine has a potent inhibitory effect on the TRPV3 channel, effectively rescuing cell death and alleviating pruritus symptoms in a mouse model with gain-of-function TRPV3 mutations, suggesting potential for treating skin inflammation.
research Implications of a Clinically Ignored Site of Acanthosis Nigricans: The Knuckles
This study observed that acanthosis nigricans is highly prevalent in Latin American youths, especially at the knuckles, and may indicate early insulin resistance even in those with a normal BMI.
research Dermatology Terminology
This article discusses the use of terminology in dermatology to describe skin diseases, but it provides no new clinical results.
research Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands
This study suggests that 1,25-dihydroxyvitamin D(3) and fibroblast growth factor 23 form a crucial axis in regulating phosphate balance, akin to its role in calcium regulation, and explores novel VDR interactions including with curcumin.
research Association of Dihydrotestosterone with Crowing Complexity Traits in Kokok Balenggek Roosters
This study found that higher dihydrotestosterone (DHT) levels are associated with reduced crowing complexity in Kokok Balenggek roosters.
research Doctor, my armpit hair has turned yellow! Malodorous yellowish axillary hair in an adolescent patient
This study described a 15-year-old male with axillary hair infection, successfully treated with topical clindamycin.
research The Fate of Trichohyalin
This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.
research Mechanism of cannabinoid incorporation in hair
This study concluded that THC and THCA incorporate into hair by a mechanism independent of hair pigmentation, likely influenced by indirect deposition via sebum and skin.
research Analysis of epidermal entry in experimental cutaneous Bacillus anthracis infections in mice
In this study, researchers observed that epidermal damage may increase susceptibility to Bacillus anthracis infection, allowing it access through hair follicles and the denuded dermis in mice.
research Higher concentrations of dithranol appear to induce hair growth even in severe alopecia areata
This study reported that dithranol treatment up to 3% concentration led to hair regrowth in alopecia areata patients who had previously failed ultra-potent steroids, with regrowth observed across all severity levels.
research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.
research Cushing Syndrome from Percutaneous Absorption of 1% Hydrocortisone Ointment in Netherton Syndrome
This report describes an 11-year-old boy with Netherton syndrome who developed Cushing syndrome after using low-potency hydrocortisone ointment extensively, highlighting caution with long-term topical treatments in such conditions.
research Recent Progress and Morphological Distribution of Polydopamine-Based Biomaterials and Their Applications
This review discusses recent advances in polydopamine-based biomaterials and their growing potential in personalized medicine, but reports no new experimental results; the authors highlight both opportunities and challenges for future applications.
research Contact Dermatitis Caused by a Grass, Axonopus compressus in a Healthy Adult Male Practising Open Defaecation
This study reports a case of phytodermatitis in a 58-year-old male due to exposure to Axonopus compressus, commonly known as carpet grass, during open defecation, highlighting an unusual cause of contact dermatitis linked to sanitation practices.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research Tryptophan Missense Mutation in the Ligand‐Binding Domain of the Vitamin D Receptor Causes Severe Resistance to 1,25‐Dihydroxyvitamin D
This study found that a specific VDR amino acid substitution in children with hereditary vitamin D-resistant rickets disrupts ligand binding and gene activation but does not impair hair follicle development.
research Strontium ranelate promotes chondrogenesis through inhibition of the Wnt/β-catenin pathway
This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.
research 490 Samcyprone (diphenylcyclopropenone ointment) for the treatment of common warts
This phase 2a trial evaluated Samcyprone for common wart treatment and found that while a sensitization reaction is necessary for therapeutic response, its level does not predict wart clearance.
research Expression of mineralized tissue associated proteins: Dentin sialoprotein and phosphophoryn in rodent hair follicles
In this study, researchers found that dentin sialoprotein and phosphophoryn are present in rat and mouse hair follicles, suggesting these proteins may play a role in hair follicle development, similar to their role in dentin mineralization.
research Evo Devo of the Vertebrates Integument
In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.
research Integumentary System
This study outlines the complex structure and various functions of the skin, emphasizing its role as a barrier against external insults, a sensory receptor, and its importance in vitamin D synthesis.