Chapter 28. Vitamin D: Production, Metabolism, Mechanism of Action, and Clinical Requirements

    November 2008
    Daniel D. Bikle, John S. Adams, Sylvia Christakos
    TLDR Vitamin D is important for regulating calcium, phosphate, and hair health.
    The document "Chapter 28. Vitamin D: Production, Metabolism, Mechanism of Action, and Clinical Requirements" from 2008, authored by Daniel Bikle, John Adams, and Sylvia Christakos, provided a comprehensive overview of Vitamin D's production, metabolism, and mechanism of action. It discussed how Vitamin D is transported in the blood and the internalization of its metabolites. The authors also explored Vitamin D's role in regulating calcium and phosphate metabolism, its effects on classic and nonclassical target tissues, and its immunobiology. Notably, the document highlighted the function of Vitamin D in keratinocyte, cells that produce keratin, in the epidermis and hair follicles, suggesting a potential role in hair health. Lastly, the authors considered the nutritional aspects of Vitamin D.
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