TLDR The skin protects the body, helps with immunity, senses, temperature control, and makes vitamin D.
The skin, the body's largest organ, consists of the epidermis, dermis, subcutis, and cutaneous adnexa like hair follicles and glands. It originates from the ectoderm, neuroectoderm, and mesoderm. The skin acts as a barrier against external threats, supports immunity, serves sensory and thermoregulatory functions, and is vital for vitamin D synthesis.
2 citations
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December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
37 citations
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June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
43 citations
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November 2007 in “Dermatologic Clinics” Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
16 citations
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July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
157 citations
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August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.