research Pathomechanisms of Immune-Mediated Alopecia
The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
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research Special Stains and Immunohistochemical Stains in Hair Pathology
Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.
research Spatial Transcriptomics of a Giant Pilomatricoma
The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders
Erdr1 could be a new marker for diagnosing hair loss.
research Overview Of Alopecia Areata For Managed Care And Payer Stakeholders In The United States
Alopecia areata causes hair loss and life quality issues; current treatments are often unsatisfactory, but new drugs like JAK inhibitors show promise.
research Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker
A genetic marker linked to a type of hair loss was found in most patients studied.
research Treatment of Alopecia Areata in Pre-Adolescent Children with Oral Tofacitinib: A Retrospective Study
Oral tofacitinib may effectively treat hair loss in children with alopecia areata.
research Alopecia in General Medicine
The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.
research Expression of Signaling Components in Embryonic Eyelid Epithelium
Eyelid cells share signaling components but differ in pathway activity.
research Sequential High- And Low-Dose Systemic Corticosteroid Therapy For Severe Childhood Alopecia Areata
High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.
research Hair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study
Ritlecitinib effectively improves hair growth in alopecia areata patients, regardless of hair loss pattern.
research Topical Janus Kinase Inhibitors: A Review of Applications in Dermatology
Topical JAK inhibitors may help treat some skin conditions but need more research.
research Local Treatments for Alopecia Areata: An Update
Various local treatments for alopecia areata show promise, but individualized plans and more research are needed.
research The Diagnosis and Treatment of Hair and Scalp Diseases
Hair loss requires customized treatments based on its various causes and types.
research An Update of the Pathogenesis of Frontal Fibrosing Alopecia: What Does the Current Evidence Tell Us?
The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
research Alopecia Areata: An Autoimmune Disease of Multiple Players
Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
research JAK Inhibitors for Treatment of Alopecia Areata
JAK inhibitors can effectively reverse hair loss in people with alopecia areata.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Effect of Long-Term Fluticasone Treatment on Immune Function in Horses with Heaves
Long-term fluticasone treatment does not harm the immune system in horses with heaves.
research Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration
The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
research Mesenchymal Stem Cell-Derived Exosomes for Organ Development and Cell-Free Therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Wnt Signaling and Aging-Related Heart Disorders
Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
research Cutaneous Reactions to Recombinant Cytokine Therapy
Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
research Single-Cell Transcriptomics Defines Keratinocyte Differentiation in Avian Scutate Scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research The Extracellular Matrix Dictates Regional Competence for Tumor Initiation
The extracellular matrix affects where tumors can start in the body.
research Erythematous Cutaneous Nodules Caused by Adulterated Cocaine
Talc in street cocaine can cause immune-reactive skin nodules where injected.
research CXCL12 Inhibits Hair Growth Through CXCR4
CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.
research Etiopathogenesis of Alopecia Areata
Alopecia Areata is an autoimmune condition causing hair loss, influenced by genetics, environment, and possibly improved by anti-MIF therapy, with many patients experiencing regrowth within a year.
research Tacrolimus in Dermatology
Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.