research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
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research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
research Antioxidants in Dermatology
Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
research Learning From Nudity: Lessons From The Nude Phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development
Chemokine signaling is important for hair development.
research Pro-Regenerative Hydrogel Restores Scarless Skin During Cutaneous Wound Healing
A special hydrogel helps heal skin without scars and regrows hair.
research Hair Cycle Control by Leptin as a New Anagen Inducer
Leptin, a hormone, is important for starting hair growth.
research Profile of Tofacitinib Citrate and Its Potential in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study
Apple extract called procyanidin B-2 was found to greatly increase hair growth.
research Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research The ITGB6 Gene: Its Role in Experimental and Clinical Biology
The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
research Human Placental Extract Exerts Hair Growth-Promoting Effects Through the GSK-3β Signaling Pathway in Human Dermal Papilla Cells
Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.
research Evaluation of the Efficacy of Transdermal Drug Delivery of Calcipotriol Plus Betamethasone Versus Tacrolimus in the Treatment of Vitiligo
Calcipotriol plus betamethasone with microneedling works better than tacrolimus for treating vitiligo.
research XEDAR Activates the Non-Canonical NF-κB Pathway
XEDAR triggers a specific signaling pathway in cells.
research Under Development JAK Inhibitors for Dermatologic Diseases
New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.
research Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss
Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.
research Emerging Role of ILK and ELMO2 in the Integration of Adhesion and Migration Pathways
ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
research The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells
Stress hormone CRF can cause hair loss by affecting hair growth cells and hormones.
research Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis
New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.
research TSPO Ligand Etifoxine Attenuates LPS-Induced Cognitive Dysfunction in Mice
Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.
research Serum 25-Hydroxyvitamin D Levels in Alopecia Areata, Female Pattern Hair Loss, and Male Androgenetic Alopecia in a Chinese Population
Low vitamin D levels are linked to different types of hair loss.
research Multiphoton Microscopic Imaging of Rabbit Dorsal Skin
Multiphoton microscopy effectively images rabbit skin structures in detail without staining and shows differences from human skin.
research Patient and Device Generated Variability in Platelet-Derived Growth Factors During Platelet-Rich Plasma Therapy for Hair Loss
Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.
research Perifollicular Vascularization: Cocultures and Tricultures Approaches to Study the Cross-Talk Between Microvascular Endothelial Cells, Follicle Papilla Cells, and Keratinocytes
Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
research Exploring Melatonin’s Multifaceted Role in Polycystic Ovary Syndrome Management: A Comprehensive Review
Melatonin may help manage PCOS by improving insulin sensitivity, hormone balance, and mood.
research CCR5 Blockade Shows Prevention of Alopecia Areata Development as Well as Improvement of Alopecia Areata
Blocking CCR5 can prevent and improve hair loss in alopecia areata.
research Loss of Langerhans Cells in Scar Lesion of Lichen Planopilaris Is Caused by Downregulation of Integrin αvβ6 in the Epidermal Keratinocytes
Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.
research Glycogen Metabolism and Cori Cycle in Human Hair Follicles
Human hair follicles have a unique way of using energy and might use the Cori cycle; blocking CCR5 could help treat hair loss.