Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
June 2019 in “International journal of dermatology and venereology” A man developed skin issues from cancer medication, which improved with specific treatments.
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62 citations,
October 2017 in “JAMA facial plastic surgery” Condensed nanofat with fat grafts effectively improves atrophic facial scars.
2 citations,
February 2021 in “Journal of comparative pathology” Sheep with chronic Sarcoptes scabiei dermatitis have altered keratin expression in their skin.
31 citations,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
13 citations,
June 2007 in “Journal of Dermatological Science” Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
9 citations,
July 2013 in “Experimental Dermatology” Aging reduces the ability of human hair follicle cells to form new cell colonies.
146 citations,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
11 citations,
September 2019 in “Dermatologic Surgery” A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
24 citations,
January 2019 in “Science China Life Sciences” Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
31 citations,
September 2013 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
199 citations,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
1 citations,
January 2019 in “Springer eBooks” Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
1 citations,
September 2017 in “Journal of Investigative Dermatology” Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
44 citations,
February 2023 in “Cell” Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
January 2022 in “International journal of zoology and animal biology” Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.
21 citations,
January 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
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August 2018 in “Journal of the American Academy of Dermatology” Calcipotriol may effectively treat hair loss in alopecia areata, working better in children than adults.
1 citations,
October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
4 citations,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
17 citations,
June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.
30 citations,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
55 citations,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
8 citations,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.