research Degradation of Aberrant NETs by DNases as a Therapeutic Strategy for SJS/TEN
Using DNase enzymes to break down harmful NETs could be a new treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis.
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research Characterizing The Expression Of Metabolic Markers In Alopecia Areata
The research identified unique metabolic activities in immune cells associated with hair loss in Alopecia Areata.
research Near Missed Diagnosis of Merkel Cell Carcinoma in a Young Immunocompetent Woman With a Recurrent Left-Arm Mass: A Case Report
A young woman with a rare skin cancer was diagnosed late because her symptoms were unusual for the disease.
research Two Parietal Cephaloceles In A Female Neonate
A baby girl had two brain-related growths removed and is developing normally.
research Homoeopathic Management of Polycystic Ovarian Syndrome – A Case Series
Homeopathic treatment improved symptoms of PCOS in seven patients.
research Ovarian Hilus Cell Hyperplasia and Sertoli-Leydig Cell Tumor in a Patient with Postmenopausal Virilization: A Rare Case Report
A woman's male-like physical changes were caused by two rare ovarian conditions.
research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
research A Rare Case of Ovarian Teratoma in a 15-Year-Old Labrador Bitch
A 15-year-old female labrador had a large ovarian tumor removed.
research Lef1 Expression in Fibroblasts Maintains Developmental Potential in Adult Skin to Regenerate Wounds
Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.
research Giant Bilateral Myelolipomas in a Patient with Congenital Adrenal Hyperplasia
A patient with untreated congenital adrenal hyperplasia had large benign tumors in her adrenal glands removed, improving her symptoms.
research Oral Chronic Ulcer: A Diagnostic Challenge
Diagnosing oral ulcers can be complex and requires careful examination and follow-up.
research Hair-Thread Tourniquet Syndrome of Labia: A Case Report
Removing hair wrapped around the labia quickly prevents serious tissue damage.
research Dermatologic Disorders: Congenital and Developmental Skin Conditions in Foals
Foals can have various skin issues, some genetic, immune-related, or due to infections and allergies.
research This Month in Adult Urology
The document highlights recent findings and treatments in urology, including prostate cancer diagnostics, urinary incontinence, and new therapies.
research Effect of Indole-Based Derivatives on Rats with Polycystic Ovary Syndrome
Indole-based compounds improved ovarian health in rats with PCOS, with L-Tryptophan and Tryptophol being most effective.
research Milia May Originate from the Outermost Layers of the Hair Bulge of the Outer Root Sheath: A Case Report
Milia may come from the outer part of the hair follicle.
research Commentary 2
Genetic factors play a major role in acne.
research Changes in the Nail Plate of the Elderly
Old people's nails often have problems due to body changes, more diseases, and self-care difficulties, affecting their movement and hand use.
research Regulation of Hair Growth
The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.
research Chronic Toxicity Studies of the Potential Cancer Preventive 2-(Difluoromethyl)-DL-Ornithine
The study investigated the chronic toxicity of 2-(difluoromethyl)-dl-ornithine, a potential cancer preventive agent, in rats and dogs. In rats, high dosages (400, 800, and 1600 mg/kg) over 52 weeks caused weight loss, increased platelets, alopecia, skin issues, liver necrosis, and gastric inflammation, with 400 mg/kg being the no-effect dose. In dogs, dosages of 50, 100, and 200 mg/kg led to conjunctivitis, hyperkeratosis, alopecia, and cystic intestinal crypts, but a no-effect dose was not identified. Despite these toxicities, the study suggested that lower dosages might minimize adverse effects, supporting further clinical development of the compound.
research Editorial: Retinoids — Dermatologists’ Drug of the Decade
Retinoids are important for treating skin conditions but should be used with caution due to serious side effects and risks during pregnancy.
research Measurement and Comparison of Various Androgen Levels in Women with Severe Acne, Hirsutism, and Androgenic Alopecia
Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
research Questions and Answers: Medical Inquiries and Treatments
Treatments for hair loss include estrogen therapy and special shampoos.
research The Pathological Dynamics of Androgenetic Alopecia and Its Treatment
Topical spironolactone effectively treats hair loss in women.
research Disorders of the Hair and Scalp in Children
The document concludes that various hair and scalp disorders in children have specific treatments and proper diagnosis is essential.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline
Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.
research Structural and Molecular Hair Abnormalities in Trichothiodystrophy
TTD hair brittleness is caused by multiple structural abnormalities.
research Cutaneous Manifestations of the Subtypes of Polycystic Ovary Syndrome in Korean Patients
Korean patients with PCOS often have skin problems like acne and excess hair, with different symptoms based on their specific PCOS type.
research Two Clinically Unusual Cases of Folliculotropic Mycosis Fungoides: One with and the Other without Syringotropism
Some cases of folliculotropic mycosis fungoides may progress slowly and not need aggressive treatment.