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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

The shape of fibrous scaffolds can improve how stem cells help heal skin.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.

A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.

Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.

Prolactin affects when mice shed and grow hair.

Using micro skin tissue columns improves skin wound healing and reduces scarring.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

Researchers identified genes and proteins that may influence wool thickness in sheep.

The engineered skin substitute helped grow skin with hair on mice.

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

The hair test for vitamin D could be a useful alternative to blood tests, providing a longer-term vitamin D status, but more research is needed.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Chamomile extract can protect hair from damage caused by light.

Experts agree on how to manage sugar levels and skin reactions in patients taking the cancer drug alpelisib.

Pantethine may boost the immune system's ability to fight sarcoma.