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Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

THSG from a Chinese plant helps with aging and related diseases.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Transplanted hair follicle stem cells can heal damaged rat intestines.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.

Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.

Targeting lipid metabolism can help treat advanced, resistant cancers.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.

The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

No strong link between testosterone or DHEAS levels and acne or hair loss in females.